Article in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Xiaobang ZhangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0001-0834-9018
Ruijie ZhangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-5618-0974
Yuhan ZhangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0004-7044-6224
Tao YangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0002-9702-8810
Longfei WuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0001-8114-7105
Yuan CaoLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.ORCID https://orcid.org/0009-0008-6238-7104
Jun XiaoLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.ORCID https://orcid.org/0000-0002-6077-2155
Jigang LiState Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-4395-2656
Xin GaoNational Engineering Research Center of Wheat and Maize, State Key Laboratory of Wheat Improvement, Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley, Shandong Provincial Technology Innovation Center for Wheat, Crop Research Institute, Shandong Academy of Agricultural Sciences, Jinan, 250100, China.ORCID https://orcid.org/0000-0003-2029-4547
Xinyou CaoNational Engineering Research Center of Wheat and Maize, State Key Laboratory of Wheat Improvement, Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley, Shandong Provincial Technology Innovation Center for Wheat, Crop Research Institute, Shandong Academy of Agricultural Sciences, Jinan, 250100, China.ORCID https://orcid.org/0000-0001-8267-3273
Jie LiuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-1415-3847
Mingming XinState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-4010-4165
Yuan ZongState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-0576-6614
Zhongfu NiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-4524-7720
Qixin SunState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-3819-6892
Yingyin YaoState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-4122-4118
Funding
Open Research Projects of the State Key Laboratory of Wheat Improvement KFKT202506
6 · The paper itself
Abstract
Wheat (Triticum aestivum L.) yield and quality are critically influenced by starch and seed storage protein (SSP) content. In this study, we demonstrate that the transcriptional adapter ADA2 physically interacts with histone acetyltransferase GENERAL CONTROL NONDEREPRESSIBLE 5 (GCN5) and regulates starch synthesis and SSP content in wheat grains. In ada2 mutants, reduced H3K9ac enrichment was observed in the promoter regions of key starch synthesis genes and the SSP regulator NAC019 during endosperm development. This reduction leads to lower expression levels, resulting in decreased starch content, smaller grains, reduced yield, and poor gluten quality. We also found that ADA2 contains an intrinsically disordered region 2 (IDR2) that undergoes liquid-liquid phase separation (LLPS) and forms nuclear condensates. In vitro assays, the LLPS of ADA2 is affected by GCN5 through direct interaction with IDR2, and the ratio of their concentrations determines the behavior of phase-separated condensates and HAT activity. High levels of GCN5 can dissolve ADA2 aggregates, while excessive ADA2 recruits and sequesters GCN5 into co-aggregated droplets, with lower HAT activity. This potential dynamic regulatory mechanism may facilitate the efficient promotion of transcription by the ADA2-GCN5 complex in wheat. Finally, we identified an elite haplotype of ADA2-B Hap2, which is significantly associated with grain size and weight, highlighting its potential as a candidate gene for genetic improvement of wheat yield.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Transcriptional adapter ADA2 regulates yield and end-use quality through liquid-liquid phase separation in wheat. · full record | OpenQuestion