SynthesisOral diseases2026
Investigating the Association Between Oral Hygiene and Oral Cancer: A Systematic Review and Meta-Analysis.
Synthesis in Oral diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aim to investigate the association between oral hygiene habits, including frequency of toothbrushing and regularity of dental check-ups, and oral cancer risk. MATERIALS AND
methodsA systematic review and meta-analysis was developed following the PRISMA and the MOOSE guidelines. We searched electronic databases until 4th December 2024 (CRD42021242709).
resultsA total of 15 studies were included. Overall, the results indicated that poor oral hygiene habits are potential risk factors for oral cancer. Compared to brushing once/day or more, toothbrushing < 1/day or never significantly increased the risk for oral cancer, with an OR of 1.85 (95% CI, 1.06-3.22). Toothbrushing < 2/day compared with ≥ 2/day also showed a positive association with oral cancer risk, with an OR of 1.32 (95% CI, 1.17-1.48). Irregular dental check-ups, defined as less than once a year or never, also significantly increased oral cancer risk (OR, 1.58; 95% CI, 1.29-1.92).
conclusionInfrequent toothbrushing and irregular dental check-ups are risk factors for oral cancer. Toothbrushing twice or more daily and visiting a dentist once a year could be recommended to reduce oral cancer risk. The study reinforces the importance of good oral health as a preventive measure in the control of oral cancer.
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