Evidence map›Paper›PMID 41840680›Full record

SynthesisInternational breastfeeding journal2026

Effectiveness of non-pharmacological traditional Chinese medicine therapies in promoting human milk feeding outcomes: a systematic review and network meta-analysis.

Liangliang Chu, Yanping Liu, Cuiping Xu

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in International breastfeeding journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liangliang ChuSchool of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250000, China.
Yanping LiuDepartment of Nursing, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jingshi Road 16766#, Jinan, Shandong, 250000, China.
Cuiping XuSchool of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250000, China. 1023909088@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuboptimal human milk feeding outcomes remain a significant public health concern worldwide. In recent years, non-pharmacological traditional Chinese medicine therapies have been increasingly explored as complementary strategies to conventional lactation support for improving human milk feeding outcomes.

methodsA systematic review and network meta-analysis of randomized controlled trials was conducted. PubMed, Embase, Cochrane Library, MEDLINE, CNKI, and Wanfang databases were searched from inception to 20 June 2025. Risk of bias was assessed using the Cochrane’ risk of bias tool 2.0. NMA was performed using STATA 18.0 to compare the effectiveness of different non-pharmacological traditional Chinese medicine therapies on exclusive breastfeeding rates, breast milk volume, time to lactogenesis II, and serum prolactin levels.

resultsA total of 33 randomized controlled trials involving 5710 participants were included. Network meta-analysis revealed that among the evaluated TCM interventions, massage + acupressure was the most effective in improving exclusive breastfeeding rates (surface under the cumulative ranking curve: 99.3%) and shortening time to lactogenesis II (surface under the cumulative ranking curve: 86.1%). For increasing breast milk volume (surface under the cumulative ranking curve: 96.3%) and elevating serum prolactin levels (surface under the cumulative ranking curve: 91%), acupuncture + auricular point sticking-pressing ranked highest. Additionally, standalone massage and acupressure demonstrated consistent beneficial effect across all outcomes, with surface under the cumulative ranking curve values ranging from 49.2% to 72.2%.

conclusionsMassage + acupressure and acupuncture + auricular point sticking-pressing emerged as the most effective non-pharmacological traditional Chinese medicine therapies for improving human milk feeding outcomes. Furthermore, massage and acupressure may serve as foundational therapies due to their consistent efficacy across multiple outcomes. These findings provide evidence-based guidance for clinical practice and underscore the potential role of non-pharmacological traditional Chinese medicine therapies as complementary approaches to conventional lactation support in enhancing human milk feeding outcomes.

Indexed as

Breast FeedingMedicine, Chinese TraditionalMilk, HumanAcupressureFemaleHumansLactationMassageProlactinRandomized Controlled Trials as TopicProlactinHuman milk feedingNetwork meta-analysisSystematic reviewTraditional Chinese medicine

Identifiers

PMID41840680
PMCPMC13104224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.