ArticleGenome biology2026
Centromere evolution in annual and perennial soybeans and its implication for hybridization in cultivated species.
Article in Genome biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Rise of Plant Pan-Genomes: From Genome Variation to Predictive Breeding.Advanced genetics (Hoboken, N.J.) · 2026Article
- Centromere evolution in annual and perennial soybeans and its implication for hybridization in cultivated species.Genome biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
backgroundCentromeres are comprised of repeats and centromeric specific histone H3 (CENH3), and they play essential roles in maintaining genome stability and defining chromosome karyotypes. Previous studies in monocotyledons show inter-species diversity of centromeric repeats and relatively stable transmission of CENH3 regions in polyploids and hybrids. Meanwhile, different CENH3 loading patterns exist in tetraploid cotton and soybean hybrid offsprings from their diploid donors. However, the dynamics of centromeric repeats and CENH3 regions during evolution and hybridization in soybean remain largely unknown.
resultsBy comparative analysis of centromere structure between perennial and annual soybeans, we find that retrotransposons and tandem repeats are the dominant centromeric specific repeats in perennial and annual soybeans, respectively. Both types of repeats exhibit low sequence similarity and minimal exchange during evolution, suggesting distinct mechanisms for centromere chromatin assembly. Furthermore, in perennial tetraploid soybeans, we detect the highest frequency of centromere repositioning among all reported polyploid plants when compared to their diploid progenitors. Interestingly, we identify diverse CENH3 loading patterns in F1 hybrids derived from different intra-species crosses, particularly those newly formed and parentally biased CENH3 loading. Different parental lines exhibit various capacities to induce distinct CENH3 loading patterns in F1 hybrids. Our results reveal recurrent CENH3 loading dynamics during soybean polyploidization and intra-species hybridization, suggesting active centromere reorganization during genetic transmission.
conclusionsOur findings reveal substantial turnover of centromeric repeats between perennial and annual soybeans, but also demonstrate various centromere repositioning in soybean polyploids and intra-species hybrids. This work expands our understanding in centromere biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.