Evidence map›Paper›PMID 41840653›Full record

SynthesisEnvironmental health : a global access science source2026

A systematic review of human studies assessing the health effects of unburned kerosene-based jet fuels and products across diverse populations and settings.

Veronica Carvajal, Brandon Ng, Nicole Rosendaal, Catherine M Pirkle

Abstract readSystematic Review
In one paragraph

Synthesis in Environmental health : a global access science source, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Veronica CarvajalDepartment of Public Health Sciences, University of Hawai'i at Mānoa, 1960 East-West Rd Honolulu, Hawai'i, 96822, USA. vcarvaja@hawaii.edu.
Brandon NgDepartment of Public Health Sciences, University of Hawai'i at Mānoa, 1960 East-West Rd Honolulu, Hawai'i, 96822, USA.
Nicole RosendaalDepartment of Public Health Sciences, University of Hawai'i at Mānoa, 1960 East-West Rd Honolulu, Hawai'i, 96822, USA.
Catherine M PirkleDepartment of Public Health Sciences, University of Hawai'i at Mānoa, 1960 East-West Rd Honolulu, Hawai'i, 96822, USA.

Funding

Henry M. Jackson Foundation PO# 1082378 FMP# 6322
6 · The paper itself

Abstract

objectivePetroleum hydrocarbons are significant environmental health concerns globally, due to their extensive use and environmental release, including water contamination events such as the 2021 Red Hill jet fuel spill. Research on kerosene and kerosene-based jet fuels is limited, with prior reviews often focused on occupational and post-combustion exposures. No previous systematic review has focused specifically on pre-combustion exposures. Thus, we systematically reviewed evidence of human health impacts associated with these raw fuels across all exposure settings and population groups. MATERIALS AND

methodsSearch strategies and eligibility criteria were developed and executed following PRISMA reporting guidelines and informed by OHAT procedures for systematic reviews. PubMed and Web of Science databases were searched (2017–2024) for eligible literature. Data extraction, analyses, quality assessment and risk of bias appraisals were conducted. Four reviewers participated in these processes.

resultsA total of 28 articles were included. Respiratory outcomes were frequently observed following acute kerosene ingestion, whereas neurological outcomes were common with chronic occupational, dermal and inhalation exposure to jet fuel. Evidence of gastrointestinal and dermal outcomes were also documented. Current literature did not allow outcomes with long latency to be assessed. Limited analytical studies and data heterogeneity challenge the ability to establish robust conclusions.

conclusionConsidering the global health implications of kerosene and kerosene-based jet fuel, and recent water contamination events, this review is novel and timely in its focus on unburned fuel. Current evidence on the human health consequences of these fuels is limited. We thus provide recommendations for future studies, including exposure assessment methods, study designs, and prioritization of underrepresented populations.

Indexed as

Environmental ExposureHydrocarbonsKeroseneHumansHydrocarbonsKeroseneEnvironmental healthEpidemiologyHuman healthJet fuelKerosenePetroleum hydrocarbons

Identifiers

PMID41840653
PMCPMC13085620

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.