Evidence map›Paper›PMID 41840585›Full record

ArticleBMC public health2026

Extreme temperature events and frailty progression in middle-aged and older adults: the longitudinal evidence from CHARLS.

Jie Wang, Chang Liu, Xiangyun Li, Xiuzhu Cao, Duanbin Li, Linfang Zhao

Abstract read
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Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie WangNursing Department, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou, Zhejiang, 310000, People's Republic of China.
Chang LiuWenzhou Medical University, Wenzhou, Zhejiang Province, China.
Xiangyun LiNursing Department, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou, Zhejiang, 310000, People's Republic of China.
Xiuzhu CaoNursing Department, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou, Zhejiang, 310000, People's Republic of China.
Duanbin LiDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. 22018293@zju.edu.cn.
Linfang ZhaoNursing Department, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou, Zhejiang, 310000, People's Republic of China. 3193159@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith global climate change, extreme temperature events (ETEs) are becoming more frequent and lasting longer, including heatwaves (HW) and cold spells (CS). ETEs have negative effects on human health, but its association with frailty progression is unclear.

methodsThis study utilized data from the China Health and Retirement Longitudinal Study (CHARLS) from 2015 to 2018. Frailty was assessed by the Frailty Index (FI), which is calculated using 32 items. ETEs were identified based on temperature thresholds and durations, quantified by event and day counts. The association between ETEs and FI was assessed by the difference-in-difference (DiD) method compared between baseline (2015) and follow-up (2018). Generalized linear models (GLMs) examined the association between ETEs exposure and frailty progression.

resultsThe study included 4,955 middle-aged and older participants (mean age 60.97 ± 8.82 years, 52.7% women). CS exposure was positively correlated with FI, whereas HW exposure was not. DiD analysis showed that under the CS definition (5th percentile, ≥4days duration), exposure to days (β = 0.802, 95% CI: 0.49 to 1.114, p < 0.001, in model 3) and exposure to events (β = 5.635, 95% CI: 3.276 to 7.995, p < 0.001, in model 3) were associated with FI progression during the follow-up period. As the temperature threshold for CS decreases and the duration increases, the estimates of the transitions from robust to pre-frail and frail states gradually strengthen.

conclusionsFor ETEs exposure, CS exposure increases the risk of frailty progression in middle-aged and older adults.

Indexed as

Cold TemperatureExtreme HeatFrailtyAgedChinaDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle AgedCHARLSCold spellExtreme temperature eventsFrailty progressionHeatwave

Identifiers

PMID41840585
PMCPMC13104448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.