ArticleBMC genomic data2026
Analysis of CGG repeat numbers in the FMR1 gene among women of childbearing age in Northeast Sichuan.
Article in BMC genomic data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveTo determine CGG repeat numbers in the Fragile X messenger ribonucleoprotein 1 (FMR1) gene among 1,146 women of childbearing age in Northeast Sichuan, China, and to describe regional carrier prevalence.
methodsA total of 1146 cases of women of childbearing age, voluntarily participating in FMR1 gene detection, were enrolled in this study from April 2021 to January 2024 in our outpatient clinic for regular prenatal check-ups, genetic counseling, and medical treatment for adverse pregnancy history. A triple-primer PCR approach was utilized to determine the CGG repeat numbers in the FMR1 gene among normal subjects, followed by a further examination of the CGG repeat numbers in fetuses from premutation female carriers.
resultIn a cohort of 1,146 women, two individuals had premutation alleles (57 and 97 repeat sizes), corresponding to a carrier frequency of 0.17% (2/1,146). Eight individuals had intermediate (gray zone) alleles (repeat sizes 45–54), resulting in a carrier frequency of 0.70%. The combined frequency of premutation and intermediate (gray zone) alleles was 0.87% (10/1,146). No full mutation alleles were identified.
conclusionThis cross-sectional study provides baseline data on the regional distribution of the FMR1 CGG repeat among women of childbearing age in Northeast Sichuan. The carrier rate of the premutation was 0.17%, and the frequency of intermediate alleles was 0.70%. These numbers represent regional prevalence only. Therefore, larger multicentre studies will be necessary to better characterize the distribution of carriers among Chinese populations. (Clinical trial number: Not applicable)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.