Observational studyActa anaesthesiologica Scandinavica2026
Occurrence of Hypoxemia the First Day After Trauma Assessed by Continuous Pulse Oximetry.
Observational study in Acta anaesthesiologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06256692 (Hypoxemia in the First 24 Hours After Trauma - an Observational Study), which is not on this map. Not yet cited in PubMed.
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Hypoxemia in the First 24 Hours After Trauma - an Observational Study
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10 authors.
Funding
Abstract
backgroundTrauma is a leading cause of death and disability in young adults. Although supplemental oxygen is recommended early after trauma to prevent hypoxemia, evidence regarding the occurrence and distribution of hypoxemic episodes, to raise awareness on potential clinical implications, is sparse. The aim of this study was to investigate the occurrence and daily distribution of hypoxemia within the first day of admission after trauma using continuous pulse oximetry.
methodsAdult trauma patients admitted through the trauma centre at Rigshospitalet, Denmark, between February 20 and August 24, 2024, were included in this observational study irrespective of subsequent admission department. Arterial oxygen saturation measured by pulse oximetry (SpO
resultsAmong 165 included participants, data from 155 were analyzed. Median age was 49 years (IQR 31-62), 74.8% were male, and median Injury Severity Score was 13 (IQR 9-19). In total 146 episodes were recorded, and both daytime and nighttime periods showed incidence rates of 5.1 episodes per 100 participant-hours, yielding an incidence rate ratio (IRR) of 1.01 (95% CI, 0.73-1.4; p = 0.95) between daytime and nighttime. No differences between daytime and nighttime were found in cumulative hypoxemia duration, prolonged hypoxemic episodes, or across hospital locations.
conclusionOn average, 5.1 clinically relevant hypoxemic episodes occurred per 100 participant-hours of continuous SpO EDITORIAL COMMENT: Supplementary oxygen is recommended in the early phase after trauma to prevent hypoxaemia. This single center study confirmed that clinically relevant hypoxaemic episodes occur on average five times per 100 participant-hours during the first 24 h of hospitalization following trauma, with similar incidences during both day and night. The study highligths the importance of continuous monitoring of peripheral oxygenation including if trauma patients are transferred from high-depency units to the wards.
trial registrationClinicalTrials.gov: NCT06256692.
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