Evidence map›Paper›PMID 41840294›Full record

ArticleAAPS PharmSciTech2026

Floating-Mucoadhesive Gastro-Retentive Tablets for Enhanced Oral Delivery of Glimepiride: Formulation, Optimization, and Controlled Release.

Ankita Basak, Soumyadip Ghosh, Dharmajit Pattanayak, Saumya Das

Abstract read
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In one paragraph

Article in AAPS PharmSciTech, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ankita BasakDepartment of Pharmaceutics, Calcutta Institute of Pharmaceutical Technology and Allied Health Sciences,Banitabla, Uluberia , 711316, India.
Soumyadip GhoshDepartment of Pharmaceutics, Calcutta Institute of Pharmaceutical Technology and Allied Health Sciences,Banitabla, Uluberia , 711316, India. soumyadeep271@gmail.com.ORCID http://orcid.org/0000-0003-0177-1328
Dharmajit PattanayakBengal School of Technology (A College of Pharmacy), Sugandha, Chuchura, 712102, India.
Saumya DasBengal School of Technology (A College of Pharmacy), Sugandha, Chuchura, 712102, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glimepiride (GLM), an essential sulfonylurea for type 2 diabetes management, suffers from poor solubility, variable absorption, and a narrow upper-GI absorption window, resulting in inconsistent therapeutic outcomes. To overcome these limitations, floating-mucoadhesive (FM) gastro-retentive tablets were developed using HPMC K15M, Carbopol 940P, and sodium bicarbonate to achieve prolonged gastric retention and controlled intragastric drug release. A 3

Indexed as

Delayed-Action PreparationsGastric MucosaSulfonylurea CompoundsTabletsAcrylic ResinsAdhesivenessAdministration, OralBiological AvailabilityChemistry, PharmaceuticalDrug Delivery SystemsDrug LiberationExcipientsHypoglycemic AgentsHypromellose DerivativesPolymersSodium BicarbonateAcrylic Resinscarbopol 940Delayed-Action PreparationsExcipientsglimepirideHypoglycemic AgentsHypromellose DerivativesPolymersSodium BicarbonateSulfonylurea CompoundsTabletsBuoyancyControlled releaseFloating-mucoadhesive tabletsGastro-retentive drug deliveryGlimepiride

Identifiers

PMID41840294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.