Evidence map›Paper›PMID 41840225›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

Suicidality in Parkinson's disease: a controlled study and review of literature.

Koray Yarız, Muhittin Cenk Akbostancı, Damla Sayar Akaslan, Turan Ayidaga, Ece Bayram, Rezzak Yılmaz

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Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Koray YarızDepartment of Psychiatry, Ankara University School of Medicine, Cebeci, Ankara, 06590, Turkey. korayyariz@gmail.com.
Muhittin Cenk AkbostancıDepartment of Neurology, Ankara University School of Medicine, Ankara, Turkey.
Damla Sayar AkaslanDepartment of Psychiatry, Ankara University School of Medicine, Cebeci, Ankara, 06590, Turkey.
Turan AyidagaDepartment of Psychiatry, Ankara University School of Medicine, Cebeci, Ankara, 06590, Turkey.
Ece BayramDepartment of Neurosciences, University of California San Diego, La Jolla, San Diego, CA, USA.
Rezzak YılmazDepartment of Neurology, Ankara University School of Medicine, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression and suicidality are prevalent among patients with Parkinson’s disease. The existing clinical studies provide conflicting data on the probability of suicidality in Parkinson’s disease.

objectiveTo compare suicidality in patients with Parkinson’s disease and neurologically healthy controls.

methodsThis study included 100 patients with Parkinson’s disease and 100 neurologically healthy controls. Cognitive performance was assessed using Mini-Mental State Examination. Depression severity and suicidality were evaluated using the Beck Depression Inventory and the Suicide Probability Scale, respectively. Disease-related variables, including disease duration, Hoehn-Yahr stage, levodopa equivalent daily dose, and the presence of subthalamic nucleus-deep brain stimulation, were collected for the Parkinson’s disease group.

resultsParkinson’s disease group demonstrated lower Mini-Mental State Examination scores, similar Beck Depression Inventory scores, and lower Suicide Probability Scale scores compared to controls. In the control group, higher Beck Depression Inventory scores were significantly associated with increased Suicide Probability Scale scores, indicating a relationship between more severe depression and higher suicidality. In Parkinson’s disease group, Suicide Probability Scale scores were significantly correlated with disease duration, levodopa equivalent daily dose, Hoehn-Yahr stage, and Beck Depression Inventory. Longer disease duration, more severe disease, higher levodopa equivalent daily dose levels, and greater depression severity were associated with increased suicidality. SPS scores were lower in the Parkinson’s disease group compared to controls.

conclusionDespite the presence of various risk factors, suicidality appears to be lower in Parkinson’s patients compared to controls. These findings highlight the complex interplay between Parkinson’s disease-related factors and suicidality.

Indexed as

DepressionParkinson DiseaseSuicideAgedCase-Control StudiesFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesSeverity of Illness IndexMovement disordersNeuropsychiatryParkinson's diseaseSuicidality

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.