Evidence map›Paper›PMID 41840046›Full record

ArticleScientific reports2026

Delayed goal-directed processing underlies inhibitory control challenges in adult ADHD.

Jahla B Osborne, Jacob Sellers, Han Zhang, Su Wang, Sarah Liberatore, Chandra Sripada, Priti Shah, John Jonides

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jahla B OsborneDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA. jahlao@umich.edu.
Jacob SellersDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Han ZhangDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Su WangDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Sarah LiberatoreDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Chandra SripadaDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Priti ShahDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
John JonidesDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.

Funding

Investigating interference-control in ADHD using a novel forced-response methodR21MH129909 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JONIDES, JOHN · 2023 to 2024
$429k
Horace H. Rackham School of Graduate Studies, University of Michigan Rackham Graduate Student Research GrantsNational Science Foundation 2238151NIMH NIH HHS R21MH129909
6 · The paper itself

Abstract

It is well documented that ADHD is associated with challenges in inhibitory control. However, the underlying cognitive mechanisms that give rise to these difficulties are not well established. Here, we employ a novel “forced-response” method with computational modeling to disentangle the time-dependent control of habitual and goal-directed processing in response-conflict tasks in adults with ADHD. We use a converging approach which compares individuals with ADHD against neurotypical individuals and individuals with ADHD off medication against on medication on two conflict tasks (Simon and Flanker). The forced-response method tracks moment-to-moment cognitive processing from stimulus to response, and data from this method was modeled using a computational model that distinguishes the temporal dynamics of habitual and goal-directed processes. Converging results revealed that ADHD was associated with delayed goal-directed processing but not rushed habitual processing when compared to both neurotypical individuals and to the same individuals on medication in both conflict tasks. These findings mark an important step toward elucidating the underlying mechanisms that lead to real-life challenges in inhibiting distracting information in adults with ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityGoalsInhibition, PsychologicalAdultCognitionConflict, PsychologicalFemaleHumansMaleReaction TimeYoung AdultADHDGoal-directedInhibitory controlResponse conflict

Identifiers

PMID41840046
PMCPMC13125289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.