ReviewLight, science & applications2026
Organic small-molecule NIR-II fluorophores for tumor phototheranostics.
Review in Light, science & applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pyrazine-embedded N^N^N-chelating tetracoordinate organoboron polycyclic heteroaromatics with low-lying LUMO levels and near-infrared luminescence.Chemical science · 2026Article
- Cyano-Mediated Donor-Acceptor Engineering: A Rational Strategy to Boost Charge Transfer in Carbon Dots for NIR-II Bioimaging.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Near-infrared II (NIR-II) fluorophores possess transformative potential for biomedical applications, owing to their deep-tissue penetration, reduced tissue autofluorescence, and low phototoxicity. Recent breakthroughs in molecular engineering have accelerated the development of NIR-II organic small-molecule fluorophores based on versatile scaffolds, including cyanine, boron dipyrromethene, benzobisthiadiazole, xanthene, cyano-based derivatives, and small-molecule metal complexes. This review systematically summarizes the molecular engineering strategies, photophysical properties, and structure-function relationships of NIR-II fluorophores in the last five years. We highlight recent breakthroughs in their theranostic applications, including high-resolution deep-tissue imaging and efficient phototherapeutic modalities such as photodynamic and photothermal therapy. Finally, we present forward-looking perspectives on current challenges and emerging opportunities, aiming to provide insights for promoting continued innovation and clinical translation in this rapidly advancing field.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.