Evidence map›Paper›PMID 41839539›Full record

ReviewArchives of disease in childhood. Fetal and neonatal edition2026

Current knowledge and future perspectives on management and prevention of group B streptococcus in neonates and young infants.

Andrew N Young, Konstantinos Karampatsas, Shamez N Ladhani, Theresa L Lamagni, Kirsty Le Doare, Joseph Peacock, Natasha Thorn, Paul T Heath

Abstract readReview
In one paragraph

Review in Archives of disease in childhood. Fetal and neonatal edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew N YoungInstitute for Infection and Immunity, City St George's University of London, London, UK ayoung@sgul.ac.uk.ORCID http://orcid.org/0000-0002-5579-4675
Konstantinos KarampatsasInstitute for Infection and Immunity, City St George's University of London, London, UK.
Shamez N LadhaniInstitute for Infection and Immunity, City St George's University of London, London, UK.ORCID http://orcid.org/0000-0002-0856-2476
Theresa L LamagniHealthcare-Associated Infection, Fungal, Antimicrobial Resistance, Antimicrobial Use, and Sepsis Division, UK Health Security Agency, London, UK.
Kirsty Le DoareInstitute for Infection and Immunity, City St George's University of London, London, UK.
Joseph PeacockInstitute for Infection and Immunity, City St George's University of London, London, UK.
Natasha ThornInstitute for Infection and Immunity, City St George's University of London, London, UK.
Paul T HeathInstitute for Infection and Immunity, City St George's University of London, London, UK.ORCID http://orcid.org/0000-0002-7540-7433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group B Streptococcus (GBS) remains a leading cause of neonatal sepsis and meningitis in the UK, with an incidence of around 0.9 per 1000 live births. Early-onset disease usually results from vertical transmission during delivery, while late-onset disease is also acquired through postnatal exposures. GBS disease presents as sepsis, meningitis or pneumonia and leads to death in 6% of affected infants and long-term neurodevelopmental impairment in up to a third of survivors. The current UK prevention strategy of risk-based intra-partum antibiotic prophylaxis has several limitations, including lack of impact on disease burden in infants without associated risk factors and on late-onset disease. Ongoing studies of universal antenatal GBS screening and GBS maternal immunisations, along with a new British Paediatric Surveillance Unit surveillance study to provide updated epidemiological data will help to guide policy and practice.

Indexed as

Child HealthCommunicable DiseasesEpidemiologyMicrobiologyNeonatology

Identifiers

PMID41839539
PMCPMC13422089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.