Evidence map›Paper›PMID 41839387›Full record

ArticleContemporary clinical trials2026

An adapted brief negotiation interview for alcohol and cannabis use among assault-injured emerging adults: A randomized pilot trial protocol.

Edouard Coupet, James Dodington, Gail D'Onofrio, Carla S Stover, James Dziura, Cecilio Pepe Vega, Elaine Couvertier, Erin Latham, Marcie Gawel, David A Fiellin and 2 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07070414 (Alcohol and Cannabis Use Among Assault-Injured Emerging Adults), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07070414 nanot yet recruitingnot on this mapstarted 2027, after this paper: background citation

Alcohol and Cannabis Use Among Assault-Injured Emerging Adults

TypeinterventionalSponsorYale UniversityRan2027 to 2028Enrolled50ConditionsAlcohol Misuse, Cannabis MisuseArmsBrief Negotiation Interview intervention (BNI) (adapted)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Edouard CoupetDepartment of Emergency Medicine, Yale School of Medicine, United States of America; Center for Injury and Violence Prevention, Yale New Haven Hospital, United States of America. Electronic address: Edouard.coupet@yale.edu.
James DodingtonCenter for Injury and Violence Prevention, Yale New Haven Hospital, United States of America; Department of Pediatrics, Yale School of Medicine, United States of America.
Gail D'OnofrioDepartment of Emergency Medicine, Yale School of Medicine, United States of America; Department of Medicine, Yale School of Medicine, United States of America; Department of Chronic Disease Epidemiology, Yale School of Public Health, United States of America.
Carla S StoverYale University Child Study Center, Yale School of Medicine, United States of America.
James DziuraDepartment of Emergency Medicine, Yale School of Medicine, United States of America.
Cecilio Pepe VegaCenter for Injury and Violence Prevention, Yale New Haven Hospital, United States of America.
Elaine CouvertierCenter for Injury and Violence Prevention, Yale New Haven Hospital, United States of America.
Erin LathamCenter for Injury and Violence Prevention, Yale New Haven Hospital, United States of America.
Marcie GawelCenter for Injury and Violence Prevention, Yale New Haven Hospital, United States of America.
David A FiellinDepartment of Emergency Medicine, Yale School of Medicine, United States of America; Department of Medicine, Yale School of Medicine, United States of America; Department of Chronic Disease Epidemiology, Yale School of Public Health, United States of America.
Samantha Lew FretzDepartment of Emergency Medicine, Yale School of Medicine, United States of America.
Federico E VacaDepartment of Emergency Medicine, University of California Irvine School of Medicine, United States of America.

Funding

Alcohol and Cannabis Misuse Among Assault-Injured Emerging AdultsR34DA061051 · NIDA · YALE UNIVERSITY · PI COUPET, EDOUARD · 2025 to 2025
$770k
NIDA NIH HHS R34 DA061051
6 · The paper itself

Abstract

Emerging adults are disproportionately at risk for substance misuse and assault injury. Assault-injured emerging adults with substance misuse have increased risk of morbidity and mortality compared to those without and often receive care in the Emergency Department (ED). This manuscript describes the development of a protocol for a pilot randomized trial of an adapted brief behavioral intervention, the Brief Negotiation Interview (BNI), for use among assault-injured emerging adults with alcohol and/or cannabis misuse presenting to the ED. First, we will perform a mixed methods study of assault-injured emerging adults with alcohol and/or cannabis misuse to elicit the shared psychosocial risk factors that contribute to both alcohol and/or cannabis misuse in the context of assault injury. We will then use these data to adapt the BNI for use among assault-injured emerging adults with alcohol and/or cannabis misuse. We will evaluate the feasibility and acceptability of the adapted BNI in a randomized trial in the ED setting (N = 50). This pilot study is a critical initial step in developing an effective brief behavioral intervention for reducing alcohol and cannabis use among assault-injured emerging adults. Trial Registration Number NCT07070414.

Indexed as

Marijuana AbuseViolenceWounds and InjuriesAdolescentAdultEmergency Service, HospitalFemaleHumansMalePilot ProjectsRandomized Controlled Trials as TopicYoung AdultAlcoholAssaultBrief interventionCannabisEmergency departmentEmerging adultsInjury preventionSubstance useYoung adults

Identifiers

PMID41839387
PMCPMC13033190

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.