Evidence map›Paper›PMID 41839328›Full record

ArticleAcademic pediatrics

Intracranial Injuries in Asymptomatic Infants Undergoing Subspecialty Evaluation for Physical Abuse: A Multicenter Study.

M Katherine Henry, Rachel P Berger, Chris Feudtner, Daniel M Lindberg, Kristine A Campbell, Jing Huang, James D Anderst, Angela N Bachim, Farah W Brink, Lori D Frasier and 8 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

M Katherine HenryDivision of General Pediatrics (MK Henry), Clinical Futures, Department of Radiology, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Roberts Center for Pediatric Research, Philadelphia, Pa. Electronic address: henrym2@chop.edu.
Rachel P BergerDepartment of Pediatrics (RP Berger), UPMC Children's Hospital of Pittsburgh, Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pa.
Chris FeudtnerDivision of General Pediatrics (C Feudtner), Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.
Daniel M LindbergDepartment of Emergency Medicine (DM Lindberg), The Kempe Center for the Prevention & Treatment of Child Abuse & Neglect, University of Colorado School of Medicine, Aurora, Colo.
Kristine A CampbellDepartment of Pediatrics (KA Campbell), University of Utah, Center for Safe and Healthy Families, Primary Children's Hospital, Salt Lake City, Utah.
Jing HuangDepartment of Biostatistics (J Huang), Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
James D AnderstChildren's Mercy Kansas City (JD Anderst), University of Missouri Kansas City School of Medicine, Kansas City, Mo.
Angela N BachimDivision of Public Health Pediatrics (AN Bachim), Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Tex.
Farah W BrinkDepartment of Pediatrics (FW Brink), Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, Ohio.
Lori D FrasierDepartment of Pediatrics (LD Frasier), Penn State Hershey College of Medicine, Hershey, Pa; Penn State Hershey Medical Center (LD Frasier), Center for the Protection of Children, Hershey, Pa.
Nancy S HarperDepartment of Pediatrics (NS Harper), University of Minnesota, University of Minnesota Masonic Children's Hospital, Center for Safe and Healthy Children, Minneapolis, Minn.
Natalie LaubUniversity of California San Diego (N Laub), Rady Children's Hospital, San Diego, Calif.
John D MelvilleDivision of Child Abuse Pediatrics (JD Melville), Medical University of South Carolina, Charleston, SC.
Jenna KielyDivision of General Pediatrics and PolicyLab (J Kiely), Children's Hospital of Philadelphia, Roberts Center for Pediatric Research, Philadelphia, Pa.
Stuart W SommersDepartment of Emergency Medicine (SW Sommers), University of Colorado School of Medicine, Aurora, Colo.
Porcia VaughnDepartment of Pediatrics (P Vaughn), University of Utah, Center for Safe and Healthy Families, Primary Children's Hospital, Salt Lake City, Utah.
Jan LeonardDepartment of Biomedical and Health Informatics (J Leonard), Data Science and Biostatistics Unit, Children's Hospital of Philadelphia, Philadelphia, Pa.
Joanne N WoodDivision of General Pediatrics and PolicyLab (JN Wood), Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.

Funding

CAPNET - Building Research Capacity in Child Abuse PediatricsR24HD098415 · NICHD · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, KRISTINE A, LINDBERG, DANIEL M · 2020 to 2024
$1.8M
AHRQ HHS K08 HS028847NICHD NIH HHS R24 HD098415
6 · The paper itself

Abstract

objectiveThe reported prevalence of intracranial injuries (ICI) in asymptomatic infants undergoing physical abuse evaluations varies widely. To inform neuroimaging decisions, we sought to 1) describe ICI prevalence among asymptomatic infants evaluated for abuse, 2) assess the impact of different definitions of "asymptomatic" on ICI prevalence across different age groups, and 3) assess whether hospital-level neuroimaging rates impact prevalence of identified ICI.

methodsWe conducted a cross-sectional study of infants <12 months without seizures or altered mental status (AMS) undergoing subspecialty evaluations for physical abuse from February 2021 through December 2022 within CAPNET, a multicenter child abuse research network. We report ICI prevalence among infants without seizures or AMS and across 3 subpopulations with progressively stricter definitions of "asymptomatic."

resultsOf 1947 infants without seizures or AMS, 1513 (77.7%) underwent neuroimaging. Of these infants, 13.7% had ICI. After excluding infants with signs of blunt head injury, ICI prevalence decreased to 5.4%. After additionally excluding infants with neurologic signs or symptoms, ICI prevalence was 5.0%. With additional exclusion of infants with nonspecific symptoms, ICI prevalence was 4.7%.

conclusionsICI prevalence in asymptomatic infants depends upon the definition of "asymptomatic". When strictly defined, asymptomatic ICI occurs in approximately 1 in 21 infants undergoing evaluations for abuse. Among infants without signs of blunt head trauma, infants <6 months have a higher risk of ICI compared to older infants.

Indexed as

Child AbuseCraniocerebral TraumaCross-Sectional StudiesFemaleHumansInfantInfant, NewbornMaleNeuroimagingPrevalenceabusive head traumaCAPNETchild physical abusediagnostic imagingoccult head trauma

Identifiers

PMID41839328
PMCPMC13552369

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.