Evidence map›Paper›PMID 41838900›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Shared competence forms the basis of gill arch and paired fin serial homology.

Michael T C Wen, Victoria E Prince, J Andrew Gillis

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael T C WenCommittee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-4391-8511
Victoria E PrinceCommittee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, IL 60637.ORCID 0000-0001-5810-7300
J Andrew GillisCommittee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, IL 60637.ORCID 0000-0003-2062-3777

Funding

American Heart Association Predoctoral Fellowship 25PRE1362838NSF (NSF) IOS2433267NSF (NSF) IOS2433268O'Brien-Hasten Fellowship from the University of Chicago N/AOwens Family Foundation (Owens Foundation) N/AUniversity of Chicago Biological Sciences Division Dean's International Student Fellowship N/A
6 · The paper itself

Abstract

The origin of paired fins is an unresolved controversy in vertebrate evolutionary biology. Karl Gegenbaur famously proposed that paired fins evolved by the transformation of a gill arch, but this hypothesis remains largely unsupported by the fossil record. Also, seemingly at odds with gill arch-paired fin serial homology are their distinct embryonic origins from neural crest and lateral plate mesoderm, respectively. We have previously shown that skate gill arch skeletal elements may derive solely from neural crest, or from a mixture of neural crest and mesoderm, and we have shown that skate gill arches and jawed vertebrate fins/limbs share several molecular patterning mechanisms. Here, we show in the little skate (

Indexed as

Animal FinsBranchial RegionGillsSkates, FishAnimalsBiological EvolutionBody PatterningMesodermNeural Crestcompetenceevolutionlateral plate mesodermneural crestserial homology

Identifiers

PMID41838900
PMCPMC13012053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.