ArticleRespiration; international review of thoracic diseases2026
The Effect of Body Position on Responses to Rapid Bilateral Anterolateral Magnetic Phrenic Nerve Stimulation in Healthy Humans (PosiStim).
Article in Respiration; international review of thoracic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionMechanical ventilation can induce lung injury and diaphragmatic dysfunction. Diaphragmatic activation via rapid bilateral anterolateral magnetic phrenic nerve stimulation (rBAMPS) may attenuate both conditions. Given a change in body position during mechanical ventilation alters patient prognosis, this study compared inspiratory responses and side effects to rBAMPS in different body positions in healthy volunteers.
methodsA total of 17 healthy participants underwent three blocks of 1-s rBAMPS at 25 Hz starting at 20% of maximal stimulator output with increases in 10% increments (until participant cessation or 100%) while lying semirecumbent, lying supine, and while seated. Esophageal and gastric balloon catheters were used to assess transdiaphragmatic pressure (P
resultsBody position significantly affected both V
conclusionrBAMPS could produce physiological resting breathing in semirecumbent, supine and sitting positions. The semirecumbent position may optimize the stimulus to the diaphragm, while the supine position may limit V
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