Evidence map›Paper›PMID 41838598›Full record

Observational studyBlood transfusion = Trasfusione del sangue

Impact of 1- and 2-unit red blood cell transfusions on continuously monitored vital signs: a longitudinal study.

Kevin M Trentino, Adam Lloyd, Kevin Murray, Grant Waterer, Shannon L Farmer, Michael F Leahy, Wayne B Dyer, Jonathon Burcham, Tim Bowles, Wendy N Erber

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Blood transfusion = Trasfusione del sangue. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kevin M TrentinoEast CareConnect, East Metropolitan Health Service, Perth, Australia.
Adam LloydEast CareConnect, East Metropolitan Health Service, Perth, Australia.
Kevin MurraySchool of Population and Global Health, The University of Western Australia, Perth, Australia.
Grant WatererMedical School, The University of Western Australia, Perth, Australia.
Shannon L FarmerDiscipline of Surgery, Medical School, The University of Western Australia, Perth, Australia.
Michael F LeahyMedical School, The University of Western Australia, Perth, Australia.
Wayne B DyerDiscipline of Surgery, Medical School, The University of Western Australia, Perth, Australia.
Jonathon BurchamEast CareConnect, East Metropolitan Health Service, Perth, Australia.
Tim BowlesEast CareConnect, East Metropolitan Health Service, Perth, Australia.
Wendy N ErberSchool of Biomedical Sciences, The University of Western Australia, Perth, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe measured trends in continuous vital sign parameters and hemoglobin concentration in adult patients before and after 1- and 2-unit red cell (RBC) transfusions. MATERIALS AND

methodsA multi-center longitudinal study of 72 patients connected to a remote continuous monitoring service transfused 1 or 2 RBC units. Primary outcome was changes in heart rate (HR), respiratory rate (RR), and oxygen saturation (SpO

resultsFifty-one patients received 1 RBC unit, 21 received 2 units. During the 10-hour pre-single-unit transfusion period, there were no clinically meaningful trends in HR (0.05, 95% CI, -0.36 to 0.46), RR (0.13, 95% CI, 0.02 to 0.25), or SpO DISCUSSION: Despite hemoglobin concentration declines pre-single and double-unit RBC transfusion, and expected increases post-transfusion, there were no clinically meaningful trends in vital signs in the 10 hours before single- or double-unit transfusion or changes in trend in vital signs 24 hours post-transfusion.

Indexed as

Erythrocyte TransfusionHeart RateHemoglobinsVital SignsAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedMonitoring, PhysiologicMulticenter Studies as TopicOxygen SaturationRandomized Controlled Trials as TopicRespiratory RateHemoglobins

Identifiers

PMID41838598
PMCPMC13155952

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.