Evidence map›Paper›PMID 41838315›Full record

ArticleApplied psychophysiology and biofeedback2026

A Smart HRV-Guided Respiratory Biofeedback System for Combined Respiratory and Psychological Recovery During COVID-19 Oxygen Weaning.

Mohanad A Deif, Mohamed A Hafez, Sally Mohammed Farghaly Abdelaliem, Mohammad Khishe

Abstract read
PubMed Publisher
In one paragraph

Article in Applied psychophysiology and biofeedback, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohanad A DeifResearch Institute of Sciences and Engineering, University of Sharjah, Sharjah, United Arab Emirates.
Mohamed A HafezFaculty of Engineering, INTI International University, Nilai, Malaysia.
Sally Mohammed Farghaly AbdelaliemDepartment of Nursing, College of Allied Health Sciences, Kuwait University, Kuwait.
Mohammad KhisheDepartment of Electrical Engineering, Imam Khomeini Naval Science University of Nowshahr, Nowshahr, Iran. m_khishe@alumni.iust.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has placed substantial pressure on intensive care units (ICUs), particularly in managing patients who require oxygen therapy and must be safely weaned from it. This study evaluated an HRV-guided respiratory biofeedback program as a non-pharmacological method to reduce respiratory discomfort and psychological distress during oxygen weaning in COVID-19 patients. A non-randomized quasi-experimental study was conducted with 80 ICU patients at Albehera Hospital, Beheira, Egypt. Patients were allocated to either a biofeedback group ([Formula: see text]) or a control group ([Formula: see text]). Both groups received standard oxygen-weaning care and routine nursing support, but only the biofeedback group received structured sessions combining diaphragmatic breathing with heart rate variability based respiratory training. The Respiratory Distress Observation Scale (RDOS) and the Depression Anxiety Stress Scale (DASS-21) were administered before and after the intervention. After adjusting for baseline scores, the biofeedback group demonstrated a markedly larger reduction in RDOS scores (from 14.48 to 4.23; [Formula: see text]) and significant improvements in DASS-21 depression, anxiety, and stress subscales ([Formula: see text]), whereas the control group showed only minimal changes. These findings suggest that HRV-guided respiratory biofeedback may enhance both respiratory comfort and psychological well-being during oxygen weaning in COVID-19 patients and could serve as a valuable adjunct to standard ICU care. Further randomized controlled trials are warranted to confirm these results and guide clinical implementation.

Indexed as

COVID-19Heart rate variabilityIntensive care unitOxygen therapy weaningRespiratory biofeedback

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.