Evidence map›Paper›PMID 41838280›Full record

ArticleMedical & biological engineering & computing2026

AortaExplorer: AI-driven analysis of the aorta in CT images.

Rasmus R Paulsen, Linnea Hjordt Juul, Michael Huy Cuong Pham, Jørgen Tobias Kühl, Klaus Fuglsang Kofoed, Kristine Aavild Sørensen, Josefine Vilsbøll Sundgaard

Abstract read
In one paragraph

Article in Medical & biological engineering & computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rasmus R PaulsenDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark.
Linnea Hjordt Juul *Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark.
Michael Huy Cuong Pham *Department of Cardiology and Radiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Jørgen Tobias KühlDepartment of Cardiology and Radiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Klaus Fuglsang KofoedDepartment of Cardiology and Radiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Kristine Aavild SørensenDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark.
Josefine Vilsbøll SundgaardDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark. josh@dtu.dk.ORCID http://orcid.org/0000-0003-2872-4660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We introduce AortaExplorer, an open-source, fully automated AI-driven framework for end-to-end aortic analysis from computed tomography angiography (CTA) scans. AortaExplorer extracts established biomarkers, such as diameters across anatomical segments, and introduces novel metrics, including aortic tortuosity. Diameter measurements were validated against expert manual readings in more than 10,000 CTA scans from Danish population cohorts, demonstrating high accuracy. The computed descending aortic tortuosity index aligns with trends reported in previous studies, confirming its increase with age. By reducing analysis time from approximately 15 minutes per case to under five minutes, AortaExplorer enables efficient, reproducible assessment of aortic morphology at scale. This tool supports clinical research and large cohort studies by combining state-of-the-art segmentation performance with extensive visualization and quantitative reporting.

Indexed as

AortaArtificial IntelligenceComputed Tomography AngiographyImage Processing, Computer-AssistedTomography, X-Ray ComputedAgedAlgorithmsFemaleHumansMaleMiddle AgedAorta analysisComputed tomographyLandmark detectionSegmentation

Identifiers

PMID41838280
PMCPMC13132940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.