Evidence map›Paper›PMID 41838138›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Twenty years of endoscopic dacryocystorhinostomy: evolution of surgical technique and outcomes in a high-volume tertiary center.

Luca Malvezzi, Francesco Giombi, Giovanna Muci, Carla Cantaffa, Egidio Serra, Luca Cerri, Giulio Sandri, Alessia Sabatino, Alberto Paderno, Domenico Villari and 5 more

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luca MalvezziOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Francesco GiombiOtorhinolaryngology Head & Neck Surgery Unit, Casa di Cura Humanitas San Pio X, Via Francesco Nava 31, Milan, 20159, Italy. francesco.giombi@humanitas.it.ORCID http://orcid.org/0000-0002-6867-5835
Giovanna MuciOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Carla CantaffaOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Egidio SerraOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Luca CerriOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Giulio SandriOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Alessia SabatinoOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Alberto PadernoOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Domenico VillariOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Fabio FerreliOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Alessandra Di MariaDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan, 20090, Italy.
Mario R RomanoDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan, 20090, Italy.
Giuseppe SprianoOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.
Gian Marco PaceOtorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a 20-year experience with endonasal endoscopic dacryocystorhinostomy (EE-DCR) in a high-volume tertiary center for distal nasolacrimal duct obstruction (NLDO), and to evaluate temporal trends in surgical techniques and outcomes.

methodsThis retrospective, single-center study included consecutive adults who underwent EE-DCR between 2004 and 2024. Collected data included the surgical approach to the lacrimal sac (anterior vs. posterior), use of powered instrumentation, use of lacrimal transillumination, operative time, postoperative complications, and duration of bicanalicular stenting. Outcomes were assessed at 6 months (T1) and 12 months (T2). Surgical success was classified as anatomical, defined as patency on lacrimal irrigation, and functional, defined as resolution of epiphora. Sensitivity analyses were conducted for procedures performed after 2014 to limit learning-curve effects and reduce confounding.

resultsA total of 440 patients underwent 600 EE-DCRs (bilateral: 160/440, 36.4%). Over the study period, surgical practice shifted toward routine adoption of posterior access and powered instrumentation, whereas transillumination was progressively abandoned. Surgical failure significantly decreased in the second decade (≤ 2014: T1 = 49/196, T2 = 55/196; >2014: T1 = 47/404, T2 = 51/353; p < 0.001). Mean operative time also declined (≤ 2014: 33.33 ± 16.19 min; >2014: 29.13 ± 11.46 min; p = 0.019). Sensitivity analyses confirmed higher success rates with powered techniques and shorter procedures with posterior approaches, independent of confounders. Complication rates remained low and stable across decades.

conclusionsOver 20 years, progressive refinement and standardization of EE-DCR resulted in improved surgical efficacy and shorter operative times without increased morbidity. In a large cohort with frequent concomitant sinonasal disease, EE-DCR proved to be safe, effective, and versatile.

Indexed as

DacryocystorhinostomyEndoscopyLacrimal Duct ObstructionAdultAgedFemaleHospitals, High-VolumeHumansMaleMiddle AgedNasolacrimal DuctOperative TimePostoperative ComplicationsRetrospective StudiesStentsTertiary Care CentersDCREndoscopic dacryocystorhinostomyLacrimal drainage systemNasolacrimal duct obstructionPosterior EE-DCRRhinology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.