Evidence map›Paper›PMID 41837941›Full record

ArticleJACC. Case reports2026

Percutaneous Mechanical Aspiration Revealing Lambl's Excrescences Initially Suspected as Papillary Fibroelastomas.

James F Howick, Carlos Vergara Sanchez, S Michael Gharacholou, Kyle Klarich, Melanie Bois, Prajwal Reddy, Abdallah El Sabbagh

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James F HowickDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Carlos Vergara SanchezDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
S Michael GharacholouDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Kyle KlarichDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Melanie BoisDepartment of Cardiovascular Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Prajwal ReddyDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Abdallah El SabbaghDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA. Electronic address: ElSabbagh.Abdallah@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mobile valvular echodensities such as papillary fibroelastomas (PFEs) and Lambl's excrescences can appear similar on imaging yet differ markedly in management. PFEs are typically resected to prevent embolic events, whereas Lambl's excrescences are benign and not treated surgically. We report 2 high-surgical risk patients with mobile aortic valve lesions presumed to be PFEs who underwent percutaneous mechanical aspiration. Both procedures achieved safe lesion debulking without complication, and histopathologic analysis revealed Lambl's excrescences rather than PFEs. These first-in-human cases demonstrate that percutaneous mechanical aspiration can serve both diagnostic and therapeutic purposes, providing definitive tissue characterization and potentially sparing patients unnecessary surgery.

Indexed as

aortic valveimagingstroke

Identifiers

PMID41837941
PMCPMC13112569

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.