Evidence map›Paper›PMID 41837907›Full record

ArticleAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics2026

Effects of Herbst and Pendex appliances treatment on the upper airway: A cone-beam computed tomography analysis.

Ward Kyle, Jiahui Madelaine Li, Brianna Tucker, Sam Kadan, Andrew S Wiemken, Bruno Saconi, Brendan T Keenan, Richard J Schwab, Chun-Hsi Chung, Hyeran Helen Jeon

Abstract readComparative Study
In one paragraph

Article in American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ward KyleSchool of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Jiahui Madelaine LiDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Brianna TuckerDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Sam KadanDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa; Private Dental Orthodontic Practice, Chalfont, Pa.
Andrew S WiemkenDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa.
Bruno SaconiDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa.
Brendan T KeenanDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa.
Richard J SchwabDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa.
Chun-Hsi ChungDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Hyeran Helen JeonDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa. Electronic address: hjeon@upenn.edu.

Funding

MicroRNAs as Biomarkers for Obstructive Sleep ApneaP01HL160471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Allan I Pack · 2023 to 2026
$11.9M
NHLBI NIH HHS P01 HL160471
6 · The paper itself

Abstract

introductionClass II functional appliances are widely used to treat skeletal Class II malocclusion in growing patients, whereas molar distalization is often employed for dental Class II malocclusion. However, the impact of these treatment modalities on upper airway dimensions remains controversial. This study examines the effects of Herbst appliance treatments on the upper airway changes compared with the Pendex appliance in adolescent patients with Class II malocclusion.

methodsCone-beam computed tomography (CBCT) scans of 50 patients with Class II malocclusion were obtained from a private orthodontic office (Chalfont, Pa). Twenty-five patients were treated with Herbst appliances (12.16 ± 1.89 years; 13 males and 12 females) and 25 patients with Pendex appliances (11.72 ± 1.22 years; 12 males and 13 females). Measurements were taken for volume, length, and cross-sectional areas of the total, retropalatal, and retroglossal upper airway. CBCTs were taken at baseline (T1), after appliance removal (T2), and from final records after fixed edgewise appliance treatment (T3) (T1-T3: 41.11 ± 9.95 months for Herbst appliances and 44.81 ± 9.63 months for Pendex appliances). In addition to 3-dimensional CBCT analysis, 2-dimensional measurements were performed and compared with a Class II untreated control group comprising 25 age- and sex-matched patients from the American Association of Orthodontists Foundation Bolton-Brush Craniofacial Growth Legacy Collection. Differences across time points within groups were assessed using repeated-measures analysis of variance test, whereas between-group differences at individual time points and for changes from T1 to T3 were evaluated using independent-samples t tests adjusted for baseline (T1) outcome values and follow-up duration.

resultsFrom T1 to T3, both the Herbst and Pendex groups showed a significant increase in total upper airway volume and length. However, the magnitude of these changes did not differ significantly between the 2 groups. In the 2-dimensional analysis, no significant differences were observed among the Herbst, Pendex, and untreated control groups in airway area changes from T1 to T3.

conclusionsBoth the Herbst and Pendex appliances resulted in comparable increases in total upper airway volume and length in adolescent patients with Class II malocclusion, primarily attributable to normal growth.

Indexed as

Cone-Beam Computed TomographyMalocclusion, Angle Class IIOrthodontic Appliances, FunctionalPharynxAdolescentCephalometryChildFemaleHumansMaleOrthodontic Appliance DesignTooth Movement Techniques

Identifiers

PMID41837907
PMCPMC13310129

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.