Evidence map›Paper›PMID 41837842›Full record

ArticleeLife2026

Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse brain.

Anisa Azatovna Gumerova, Georgii Pevnev, Funda Korkmaz, Uliana Cheliadinova, Guzel Burganova, Darya Vasilyeva, Liam Cullen, Orly Barak, Farhath Sultana, Weibin Zhou and 9 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Anisa Azatovna GumerovaInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-1449-4000
Georgii PevnevInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0003-2015-9310
Funda KorkmazInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-9174-8369
Uliana CheliadinovaInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0009-0007-2308-4824
Guzel BurganovaInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-7204-7268
Darya VasilyevaInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0009-0007-5121-9618
Liam CullenInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Orly BarakInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-3041-2343
Farhath SultanaInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0003-4186-3390
Weibin ZhouInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Steven Lee SimsInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-1636-084X
Emily WeissInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Victoria LaurencinInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0009-0006-0801-6471
Tal FrolingerInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-2066-6649
Se-Min KimInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Ki A GoosensInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-5246-2261
Tony YuenInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Mone ZaidiInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0001-5911-9522
Vitaly RyuInstitute for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0001-8068-4577

Funding

Targeting FSH for the Therapy of Osteoporosis, Obesity and NeurodegenerationU19AG060917 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLIFFORD JAMES ROSEN, Mone Zaidi · 2019 to 2026
$29.0M
NIH HHS AG071870NIH HHS AG073148NIH HHS AG074092NIH HHS DK113627NIH HHS U19 AG060917
6 · The paper itself

Abstract

Vasopressin (AVP), a nonapeptide synthesized predominantly by magnocellular hypothalamic neurons, is conveyed to the posterior pituitary via the pituitary stalk, where AVP is secreted into the circulation. Known to regulate blood pressure and water homeostasis, it also modulates diverse social behaviors, such as pair bonding, social recognition, and cognition in mammals, including humans. Importantly, AVP modulates social behaviors in a sex-specific manner, perhaps due to sex differences in the distribution in the brain of AVP and its main receptor AVPR1a. There is a

Indexed as

BrainReceptors, VasopressinVasopressinsAnimalsFemaleMaleMiceSex CharacteristicsAVPR1a receptor, mouseReceptors, VasopressinVasopressinsAVPR1abrain atlasmouseneurosciencevasopressin

Identifiers

PMID41837842
PMCPMC12991652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.