ReviewmBio2026
mGem: Facilitated fermentation-an underappreciated mode of energy conservation.
Review in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Genome-wide fitness profiling reveals flagellar rotation as an energetic liability during anaerobic maintenance inbioRxiv : the preprint server for biology · 2026Article
- Oxygen-dependent partitioning of acetate assimilation via Acs and AckA-Pta pathways inJournal of bacteriology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Here, we introduce a new name into the bacterial energy conservation lexicon: facilitated fermentation. This name is necessary because the more familiar terms "respiration" and "fermentation" do not adequately describe how electron balancing is coupled to energy conservation for organisms that engage in this metabolism. Facilitated fermentation is when ATP is predominantly made via a substrate-level pathway that is redox-coupled to a terminal electron acceptor reduced outside of the cell. The coupling is often facilitated by an extracellular electron shuttle or outer membrane protein that shuttles electrons from the electron transport chain to the extracellular acceptor. Naming facilitated fermentation is timely because it has recently been demonstrated to support both growth and non-growth states in bacteria that are important in nature and disease. We hope that the introduction of this term will inspire future research to evaluate the extent of facilitated fermentation's prevalence and impact in the microbial world and beyond.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.