Evidence map›Paper›PMID 41837604›Full record

ArticleAmerican journal of epidemiology2026

Changes in financial well-being and memory function and decline in middle-aged and older adults.

Katrina L Kezios, Jordan Vo, Zihan Chen, Sarah Weber, Allison E Aiello, Adina Zeki Al Hazzouri

Abstract read
In one paragraph

Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katrina L KeziosDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.ORCID 0000-0001-7115-032X
Jordan VoWeinberg College of Arts and Sciences, Northwestern University, Chicago, IL, United States.
Zihan ChenDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.
Sarah WeberDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Allison E AielloDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.
Adina Zeki Al HazzouriDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Expanding the RAND HRS Data System to Better Support Research on Health and AgingR01AG073289 · NIA · RAND CORPORATION · PI SUSANN ROHWEDDER, DAVID R. WEIR · 2022 to 2026
$3.7M
Immunosenescence, socioeconomic disadvantage and dementia in the US aging populationR01AG075719 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Allison E Aiello, Grace A Noppert · 2022 to 2026
$3.6M
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortR00AG084769 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Katrina L Kezios · 2025 to 2026
$489k
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortK99AG084769 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEZIOS, KATRINA L · 2024 to 2025
$263k
NIA NIH HHS K99 AG084769NIA NIH HHS K99AG084769 and R00AG084769NIA NIH HHS NIA U01AG009740 and NIA R01AG073289NIA NIH HHS R00 AG084769NIA NIH HHS R01 AG073289NIA NIH HHS R01AG075719NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

Many older adults experience financial insecurity. While prior studies link lower later-life socio economic status, financial stress, and financial shocks to worse cognitive outcomes, limited research has examined how dynamic changes in financial well-being-a multidimensional measure of financial circumstances-influence cognitive aging. Here, we examined associations between changes in financial well-being and memory outcomes among 7676 adults aged 50+ in the Health and Retirement Study ("HRS," 2010-2020). We developed and validated an 8-item index of poor financial well-being using existing HRS survey items aligned with domains from the Consumer Financial Protection Bureau's Financial Well-Being Scale. In confounder-adjusted linear mixed-effects models, we estimated the associations of average financial well-being and significant improvements or worsening in financial well-being over 4 years, with changes in memory z scores calculated biennially from 2016 to 2020. Each 1-point worsening in average financial well-being was associated with poorer memory function (β = -0.009 SD, 95% CI, -0.020 to 0.003) and accelerated decline (β = -0.007 SD/year, 95% CI, -0.010 to -0.003). Associations were largest for participants with significant worsening of financial well-being and for those aged ≥65 at baseline. Results were robust to sensitivity analyses addressing potential reverse causation and attrition. These findings suggest that midlife and later-life declines in financial well-being may contribute to accelerated cognitive aging.

Indexed as

Cognitive AgingCognitive DysfunctionFinancial StressMemoryAgedFemaleHumansMaleMiddle AgedSocioeconomic FactorsUnited Statescognitive agingeconomic insecurityfinancial well-beingmeasurementmemory decline

Identifiers

PMID41837604
PMCPMC13343384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.