ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Evidence of histamine release in response to both aerobic and resistance exercise: histamine metabolites as biomarkers.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Histamine released within skeletal muscle facilitates sustained postexercise vasodilation and contributes to the development of training adaptations. Quantifying the histamine response is challenging because histamine is rapidly broken down and metabolized. Thus, we explored the use of histamine's metabolites, 1-methylhistamine and 1-methylimidazole acetic acid, as biomarkers of the histamine response to exercise. We hypothesized that plasma concentrations and urinary production of these metabolites would increase following aerobic and resistance exercise. Twelve (1 female, 11 male) participants (V̇o
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