ArticleMicrobiology spectrum2026
Gut microbiota dysbiosis and amino acid metabolic dysregulation in children with allergic rhinitis complicated by constipation.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Integrated untargeted metabolomics and lipidomics reveals functional- and taste-related compounds in stir-friedFrontiers in nutrition · 2026Article
- Article
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Authors and funding
7 authors.
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Abstract
This study investigates the pathogenesis of constipation in children with allergic rhinitis (AR) by analyzing gut microbiota (GM) composition and fecal metabolites. We enrolled 21 AR children (AR group) and 16 AR children with constipation (ARFC group), performing absolute quantitative 16S rRNA sequencing and non-targeted metabolomics on fecal samples. The key findings are as follows: (i) The ARFC group exhibited significantly elevated IMPORTANCE: Allergic rhinitis (AR) is a common allergic disorder in children, often accompanied by gastrointestinal symptoms such as constipation, yet the underlying mechanisms remain poorly understood. This study reveals that constipation in AR children is associated with specific gut microbiota alterations-particularly an increase in CLINICAL TRIALS: This study is registered with Chinese Clinical Trial Registry as ChiCTR2400085982.
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