Evidence map›Paper›PMID 41837237›Full record

ReviewBJR open2026

Bridging the gap between radiologic and manometric criteria to diagnose esophageal motility disorders: a pictorial review for radiologists.

Ahmed O El Sadaney, D Chamil Codipilly, David J Bartlett, Kristina T Flicek, Michael L Wells, Safa Hoodeshenas, Jay Heiken, Karthik Ravi, Joel G Fletcher, Avinash K Nehra

Abstract readReview
In one paragraph

Review in BJR open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmed O El SadaneyDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
D Chamil CodipillyDepartment of Gastroenterology, Mayo Clinic, Rochester, MN 55905, United States.
David J BartlettDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Kristina T FlicekDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Michael L WellsDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Safa HoodeshenasDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Jay HeikenDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Karthik RaviDepartment of Gastroenterology, Mayo Clinic, Rochester, MN 55905, United States.
Joel G FletcherDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Avinash K NehraDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.ORCID https://orcid.org/0000-0003-2051-6832

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysphagia is defined as a subjective sensation of difficulty swallowing and can result from oropharyngeal or esophageal etiologies based upon patient symptoms. Dysphagia affects approximately 16% of adults in the general population, with prevalence increasing with age. Esophagogastroduodenuoscopy (EGD) is initially performed to assess for structural abnormalities resulting in esophageal dysphagia. However, if EGD reveals no pathologic abnormalities, high-resolution manometry (HRM) and barium esophagography are performed in order to assess for underlying causes of dysmotility. Esophageal motility disorders (EMDs) are an underrecognized cause of dysphagia and can be characterized by impaired esophageal peristalsis or lower esophageal sphincter dysfunction. High-resolution manometry (HRM) measures key metrics such as integrated relaxation pressure (IRP), which is the deglutitive relaxation across the LES, and metrics of esophageal body peristalsis based on distal contractile integral (DCI) and distal latency (DL). The Chicago Classification version 4 (CCv4.0), published in 2021, provides a standardized classification scheme for differentiating EMDs using metrics from HRM. Additionally, barium esophagography has remained an important adjunctive diagnostic modality, as this may identify strictures, neoplasms, or hiatal hernias, but can also identify major motility disorders such as achalasia and distal esophageal spasm. The combined use of HRM with timed barium esophagram can enhance the diagnostic accuracy of EMDs, particularly when HRM demonstrates inconclusive findings. Therefore, radiologists should be familiar with how imaging findings from barium esophagram integrate with findings noted on HRM. The aim of this review is to highlight the findings of EMDs noted on HRM in conjunction with barium esophagography, thereby illustrating characteristic patterns of primary and secondary EMDs.

Indexed as

esophageal motility disordersesophagusfluoroscopylower esophageal sphinctermanometry

Identifiers

PMID41837237
PMCPMC12987765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.