SynthesisFrontiers in endocrinology2026
Association between triglyceride glucose index and risk of acute kidney injury in critically ill patients: a systematic review and meta-analysis.
Synthesis in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Association of the Triglyceride-Glucose Index with Contrast-Associated Acute Kidney Injury in Patients with Atherosclerotic Renal Artery Stenosis.Journal of cardiovascular development and disease · 2026Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute kidney injury (AKI) is a common and serious complication among critically ill patients. The triglyceride-glucose (TyG) index, a simple surrogate marker of insulin resistance (IR), has recently emerged as a potential predictor of AKI in this population. However, the existing evidence has not yet been systematically evaluated. Objective: To systematically evaluate the association between the TyG index and the risk of AKI in critically ill patients. Methods: A comprehensive literature search was performed across PubMed, Embase, and Web of Science from inception to October 31, 2025, for observational studies reporting the relationship of the TyG index with AKI risk among critically ill patients. Following predefined eligibility criteria, two authors independently undertook the screening process, data extraction using a standardized data collection form, and risk of bias evaluation. All statistical analyses were carried out with RevMan 5.3 and Stata 16.0. Results: A total of 18 studies involving 81,479 participants were included in the meta-analysis. The results demonstrated that a higher TyG index was significantly associated with an increased risk of AKI, with a pooled odds ratio (OR) of 1.39 (95% CI: 1.22-1.58, Conclusion: The TyG index was significantly associated with the risk of AKI in critically ill patients, with higher TyG index levels correlating with an increased risk of AKI. Systematic Review Registration: https://www.crd.york.ac.uk/prospero, identifier CRD420251232658.
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