ArticleInternational journal of surgery case reports2026
Unexpected diagnosis at laparotomy: intrahepatic splenosis mimicking hepatocellular carcinoma - a case report.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Intrahepatic splenosis (IS) is a rare benign condition developing after splenic tissue autotransplantation, usually post-trauma or splenectomy. In HBV-infected patients, it can mimic hepatocellular carcinoma (HCC), leading to misdiagnosis and unnecessary surgery. Presentation of case: A 42-year-old man with chronic HBV infection and prior splenectomy had a 4-cm hepatic lesion with arterial enhancement and venous washout, consistent with HCC. Laparotomy revealed a dark-purple mass and diaphragmatic nodules; frozen and histopathology confirmed splenic tissue. The patient recovered well and remained recurrence-free after 1 year. Discussion: IS should be considered in patients with previous splenectomy and hepatic masses to avoid misdiagnosis. Noninvasive imaging such as Tc-99m-labeled RBC scintigraphy can prevent unnecessary resections. Conclusion: Increasing awareness of IS may help prevent unnecessary liver resections in similar cases.
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