ArticleInternational journal of surgery case reports2026
Carpal tunnel syndrome caused by tophaceous gout: a case series and review of the literature.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction and importance: Carpal tunnel syndrome (CTS) secondary to gout is a rare but potentially overlooked condition in clinical practice. Early diagnosis and timely intervention are essential for restoring patient function and preventing recurrence. Case presentation: We present five cases, with two patients having bilateral tophaceous CTS and two with unilateral CTS, all attributed to gout. All patients underwent open carpal tunnel release surgery. No adverse events or recurrences were noted during the follow-up period. Clinical discussion: CTS due to tophaceous gout is rare but important, caused by urate crystal deposits leading to nerve compression and inflammation. Diagnosis may be difficult, requiring imaging in unclear cases. Surgery with tophus removal is effective, and long-term urate-lowering therapy helps prevent recurrence. Conclusion: A prior diagnosis of gout serves as an important red flag for CTS. Early diagnosis through clinical and imaging assessments can significantly enhance surgical outcomes. A comprehensive management approach ensures effective symptom relief and reduces the risk of recurrence.
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