Evidence map›Paper›PMID 41837055›Full record

ArticleInternational journal of surgery case reports2026

Col II-CS-HA cartilage biomimetic matrix gel provides a new treatment option for huge cartilage defects - a case report.

Qian-Kun Ni, Jing-Tong Lyu, Fu-You Wang, Lin Guo

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qian-Kun NiSports Medicine Center, The First Affiliated Hospital of Army Medical University, Sha Ping Ba District, Chongqing, China.ORCID https://orcid.org/0000-0002-1211-6364
Jing-Tong LyuSports Medicine Center, The First Affiliated Hospital of Army Medical University, Sha Ping Ba District, Chongqing, China.
Fu-You WangRehabilitation Medicine Department, Jiang Bei Branch Hospital of The First Affiliated Hospital of Army Medical University (The 958th Army Hospital of the Chinese People's Liberation Army), Jiang Bei District, Chongqing, China.
Lin GuoSports Medicine Center, The First Affiliated Hospital of Army Medical University, Sha Ping Ba District, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Articular cartilage injuries constitute a predominant musculoskeletal disease in athletic populations. These lesions frequently precipitate the progressive degeneration, culminating in premature career termination and increased functional impairment. However, current treatment methods for cartilage injury are not entirely satisfactory, especially for large full-thickness cartilage defects. Presentation of case: A 13-year-old male adolescent with documented high-intensity athletic engagement (training >15 hours/week) presented a huge exercise-induced full-thickness cartilage defect (6 cm Discussion: Current treatment strategies for cartilage defects, including microfracture and autologous chondrocyte implantation, demonstrate limited long-term efficacy for large full-thickness cartilage defects (>2 cm Conclusion: The case we present demonstrates the effectiveness of this Col II-CS-HA cartilage biomimetic matrix gel, which is expected to become a new effective solution for huge cartilage defects in future clinical practice.

Indexed as

biomimetic matrix gelcartilage defectcartilage regenerationtissue engineering

Identifiers

PMID41837055
PMCPMC12981881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.