ArticleFrontiers in medicine2026
A predictive nomogram for postoperative ovarian endometrioma recurrence in patients with congenital obstructive Müllerian anomalies: a retrospective study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to develop a predictive model for ovarian endometrioma (OE) recurrence in patients with congenital obstructive Müllerian anomalies (OMAs) undergoing surgical intervention. Methods: This retrospective cohort study included 139 OMA patients with histologically confirmed ovarian endometrioma undergoing complete lesion excision and anatomical reconstruction between January 2013 and December 2020. A multivariable Cox regression analysis identified recurrence predictors; a nomogram was constructed and validated via time-dependent receiver operating characteristic curve (ROC), calibration curve, and decision curve analysis. Results: The mean surgical age of 139 patients was 20.70 ± 5.81 years. Over a mean follow-up of 80.8 months, 29.5% of patients experienced OE recurrence. Cumulative recurrence rates were 1.4% (24 months), 10.1% (36 months), 27.1% (60 months), and 34.4% (120 months). In a multivariate analysis, independent risk factors for endometrioma recurrence, such as preoperative hematometra >5 cm Conclusion: This model effectively stratifies OE recurrence risk in OMA patients post-surgery, guiding personalized management. Early surgical intervention may optimize endometrioma recurrence prevention to relieve Müllerian duct obstruction combined with prolonged postoperative medical suppression.
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