Evidence map›Paper›PMID 41836918›Full record

ArticleImaging neuroscience (Cambridge, Mass.)

Diazepam alters the shape of alpha oscillations recorded from human cortex using EEG.

George M Opie, Natalie Schaworonkow, Pedro C Gordon, Dania Humaidan, Ulf Ziemann

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George M OpieDiscipline of Physiology, School of Biomedicine, The University of Adelaide, Adelaide, Australia.ORCID https://orcid.org/0000-0001-7771-7569
Natalie SchaworonkowErnst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany.
Pedro C GordonDepartment of Neurology & Stroke, Eberhard Karls University of Tübingen, Tübingen, Germany.
Dania HumaidanDepartment of Neurology & Stroke, Eberhard Karls University of Tübingen, Tübingen, Germany.
Ulf ZiemannDepartment of Neurology & Stroke, Eberhard Karls University of Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While neural oscillations are conventionally assessed via their frequency, power and phase, developing literature suggests that their shape also provides neurophysiological and functional information. However, the extent to which the shape of oscillations recorded non-invasively in humans index specific brain processes remains unclear. This study implemented a pharmaco-EEG approach to begin addressing this limitation. Resting-state EEG data were collected before and after placebo or diazepam, a positive allosteric modulator of type A γ-aminobutyric acid (GABA

Indexed as

alpha oscillationdiazepamelectroencephalographyGABAA receptorpharmaco-EEGwaveform shape

Identifiers

PMID41836918
PMCPMC12983582

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.