Evidence map›Paper›PMID 41836843›Full record

ArticleProceedings (Baylor University. Medical Center)

Treatment of breakthrough labor pain with epidural dexmedetomidine: a case series.

Abigail Blanton, Zehra Tombul, Robert Beck, Weike Tao, Allison A Mootz

Abstract readCase Reports
In one paragraph

Article in Proceedings (Baylor University. Medical Center). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abigail BlantonUniversity of Texas Southwestern Medical School, Dallas, Texas, USA.
Zehra TombulUniversity of Texas Southwestern Medical School, Dallas, Texas, USA.
Robert BeckDepartment of Anesthesiology, Parkland Health & Hospital System, Dallas, Texas, USA.
Weike TaoDepartment of Anesthesiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Allison A MootzDepartment of Anesthesiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0002-5623-3423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breakthrough labor pain, defined as the return of pain despite ongoing administration of neuraxial analgesia, poses a significant challenge within the field of obstetric anesthesia. Epidural adjunct medications may be used to enhance neuraxial block density or provide coverage to previously spared regions. Dexmedetomidine, a US Food and Drug Administration-approved selective alpha-2 adrenergic agonist, has gained attention for an off-label use as a labor epidural adjunct medication for labor analgesia. This case series highlights three cases of epidural dexmedetomidine use for breakthrough pain during labor.

Indexed as

Dexmedetomidineepidural analgesialabor painobstetrical anesthesia

Identifiers

PMID41836843
PMCPMC12981595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.