Evidence map›Paper›PMID 41836799›Full record

ArticlePakistan journal of medical sciences2026

Sensitivity and Safety of Contrast-enhanced cystosonography in diagnosis of pediatric vesicoureteral reflux after urinary tract infection.

Junping Wang, Xiaoman Wang, Bin Yang, Yali Ma, Qiang Wang

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Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Junping WangJunping Wang, Department of Functional, Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Xiaoman WangXiaoman Wang, Department of Functional, Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Bin YangBin Yang, Department of Urology Surgery, Department of Functional, Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Yali MaYali Ma, Department of Functional, Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Qiang WangQiang Wang, Department of Functional, Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the sensitivity and safety of contrast-enhanced cystosonography in the diagnosis of primary vesicoureteral reflux (VUR) after urinary tract infection (UTI) in infants. Methodology: This was a retrospective study. Infants diagnosed with VUR after UTI in Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University were selected from July 2019 to May 2024. All the infants were subjected to contrast-enhanced cystosonography and voiding cystourethrography(VCUG). The detection rate of VUR by contrast-enhanced cystosonography and VCUG, as well as the consistency of VUR classification were analyzed. Results: The proportion of VUR diagnosed by contrast-enhanced ultrasonography(CEUS) was 32.00%, which was significantly higher than 18.00% by VCUG(P< 0.05). The incidence of VUR was 38.23% and 43.75% in male and female infants, respectively, without statistically significant differences(P> 0.05). Among the male infants, the proportion of VUR diagnosed by CEUS was 20.58%, while the proportion by VCUG was 17.65%(P> 0.05). In the female infants, the proportion of VUR diagnosed by CEUS was 50.00%, which was significantly higher than 18.75% by VCUG (P< 0.05). VUR was diagnosed in 31.00% (31/100) pyelo-ureter units(PUUs) by CEUS, and in 18.00% (18/100) PUUs by VCUG, with good consistency(Kappa value, 0.547). The consistency of both methods in diagnosing VUR at different degrees was good, with higher diagnostic rates of Grade-II and III VUR. Conclusion: Both contrast-enhanced cystosonography and VCUG have high diagnostic value in the detection of infants with VUR after UTI. The value of contrast-enhanced cystosonography in the diagnosis of infants with UTI and VUR is higher.

Indexed as

Urinary tract infectionVesicoureteral refluxVoiding cystourethrographyVoiding urosonography

Identifiers

PMID41836799
PMCPMC12980346

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