Evidence map›Paper›PMID 41836788›Full record

ArticleJournal of oral microbiology2026

Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia.

Jun Hyung Cha, Sol-Ah Jeong, Byoung-Seok Ye, Insuk Lee, Bock-Young Jung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun Hyung ChaDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Sol-Ah JeongDepartment of Advanced General Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
Byoung-Seok YeDepartment of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Insuk LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Bock-Young JungDepartment of Advanced General Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Dementia poses a growing burden in the aging population, prompting the search for noninvasive biomarkers for early detection. Materials and methods: We performed shotgun metagenomic sequencing of tongue-coating samples from older adults with dementia ( Results: The analysis revealed distinct microbial compositions associated with dementia, including an enrichment of Conclusions: These results suggest that specific oral taxa and their metabolic functions are associated with cognitive status and may reflect underlying neurodegenerative processes.

Indexed as

biomarkerDementiametabolic pathwayoral microbiomeshotgun metagenomic sequencing

Identifiers

PMID41836788
PMCPMC12981268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.