ArticleJournal of advanced pharmaceutical technology & research
Effect of sperm cryopreservation and preparation before freezing-thawing process: A study of DNA fragmentation and ultrastructure.
Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Male fertility preservation can be achieved through assisted reproductive technology, in which sperm cryopreservation plays an essential role. However, the freezing-thawing process induces cellular stress, primarily through intracellular ice crystal formation, which damages membranes, organelles, and exacerbates osmotic and oxidative stress. This study aims to determine whether sperm cryopreservation and preparation affect sperm concentration and motility, cryosurvival rate (CSR), DNA fragmentation, and ultrastructure after thawing. A total of 10 human sperm samples were rapidly frozen in cryovials, with prefreeze and postthaw analyses compared against fresh controls, assessing sperm parameters, DNA fragmentation, and ultrastructure (scanning electron microscope). Statistical analysis included paired comparisons for two groups and multigroup tests with
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Registered trials
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