ArticleJournal of advanced pharmaceutical technology & research
Protective effects of the ethanolic extract from the Benjakul remedy against oxidative stress and inflammation.
Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Oxidative stress and inflammation contribute to liver damage from xenobiotics, leading to chronic diseases. The ethanolic extract of the Benjakul remedy (BJE), a traditional Thai medicine, is recognized for its potential antioxidant and anti-inflammatory effects, though scientific validation is limited. This study assessed BJE's antioxidant effects against various radicals using chemical and cellular assays, evaluated its anti-inflammatory effects by measuring inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) levels, and determined protective effects by evaluating cell viability and oxidative damage. Total phenolic content was measured colorimetrically, and compounds were identified using liquid chromatography combined with electrospray ionization quadrupole time-of-flight mass spectrometry. BJE significantly scavenged synthetic radicals, nitric oxide radicals, and lipid radicals, with IC
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