Evidence map›Paper›PMID 41836722›Full record

ArticleInternational journal of nanomedicine2026

Magnesium Oxide Nanoparticles Loaded with 6-Gingerol: A Bioinspired Approach to Anticancer, Anti-Inflammatory, and Antioxidant Therapy.

Chinnaperumal Kamaraj, Dede Heri Yuli Yanto, Vinoth Kumarasamy, Khalid A Al-Ghanim, Vetriselvan Subramaniyan, Ling Shing Wong, Cittrarsu Vetrivel

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chinnaperumal KamarajInterdisciplinary Institute of Indian System of Medicine (IIISM), Directorate of Research, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.ORCID 0000-0001-9955-9397
Dede Heri Yuli YantoResearch Center for Applied Microbiology, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia.
Vinoth KumarasamyDepartment of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan, Kuala Lumpur, Malaysia.ORCID 0000-0002-8895-1796
Khalid A Al-GhanimDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Vetriselvan SubramaniyanDivision of Pharmacology, School of Medical and Life Sciences, Sunway University, Selangor Darul Ehsan, 47500, Malaysia.
Ling Shing WongFaculty of Health and Life Sciences, INTI International University, Nilai, 71800, Malaysia.ORCID 0000-0002-5869-0804
Cittrarsu VetrivelInternational Joint Laboratory on Synthetic Biology and Biomass Biorefinery, Biofuels Institute, School of Emergency Management, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this work is to synthesize magnesium oxide nanoparticles (Gi-MgO NPs) by extracting 6-gingerol (Gi) from Methods: The physical and chemical characteristics were examined by FT-IR, HPTLC, XRD, XPS, HR-SEM, HR-TEM, EDX, and zeta potential. Proton ( Results: The Gi-loaded nanoparticles were shown to be more effective than 6-gingerol, as evidenced by their increased toxicity against the THP-1 cell line (IC Conclusion: The present investigation revealed Gi-MgO NPs significant anticancer effect and ability to cause apoptosis in malignant cells by modifying the expression of apoptosis-related genes; however, additional ex vivo and molecular mechanism studies are required.

Indexed as

Anti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsCatecholsFatty AlcoholsMagnesium OxideMetal NanoparticlesNanoparticlesApoptosisBiphenyl CompoundsCell Line, TumorCell SurvivalHumansParticle SizePicratesTHP-1 CellsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBiphenyl CompoundsCatecholsFatty AlcoholsgingerolMagnesium OxidePicrates6-gingerolanticancerGi-MgO NPsHR-TEMNMRTHP-1 cells

Identifiers

PMID41836722
PMCPMC12983165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.