Evidence map›Paper›PMID 41836613›Full record

ArticleDigital health

Safety and user perception of general-purpose large language models in pediatric healthcare: Evaluations of ChatGPT by doctors and parents.

Jing Tan, Lin Wang, Guanghai Wang, Yonghong Yang, Feiyong Jia, Xia Chi, Xiaoli Xie, Tingyu Li, Binrang Yang, Huifeng Zhang and 4 more

Abstract read
In one paragraph

Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jing TanGrowth, Development and Mental Health Center of Children and Adolescents, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Lin WangChild Healthcare Center, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Guanghai WangDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yonghong YangLaboratory of Microbiology and Immunology, National Center for Children's Health, Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Feiyong JiaDepartment of Developmental and Behavioral Pediatrics, The First Hospital of Jilin University, Changchun, China.
Xia ChiNanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, China.
Xiaoli XieChengdu Women's and Children's Central Hospital Gastroenterology Department, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Tingyu LiGrowth, Development and Mental Health Center of Children and Adolescents, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Binrang YangChildren's Healthcare and Mental Health Center, Shenzhen Children's Hospital, Shenzhen, China.
Huifeng ZhangDepartment of Pediatrics, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Min GongDepartment of Pediatrics, Richmond University Medical Center, New York, United States.
Yuxin WuDepartment of Neurosurgery, Children's Hospital of Chongqing Medical University, Chongqing, China.
Xiuyu ShiGrowth, Development and Mental Health Center of Children and Adolescents, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Li ChenGrowth, Development and Mental Health Center of Children and Adolescents, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-1766-5418

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objective: Although the internet has broadened access to medical resources, concerns persist regarding the quality and accuracy of available content. ChatGPT, a general-purpose large language model, may help bridge this gap. This study evaluates its safety and user perception in addressing pediatric healthcare queries. Methods: Nine experts independently evaluated 41 questions, with three experts assigned to each of the following topics: vitamin D (15 questions), food allergies (16 questions), and sleep problems (10 questions). Each question was answered separately by ChatGPT3.5 and ChatGPT4. Ratings were determined by expert consensus or, in cases of disagreement, the lowest rating. Additionally, 27 parents evaluated ChatGPT's responses. Results: Experts rated 73.2% of responses from ChatGPT3.5 as "completely correct" or "correct but not comprehensive," while 26.8% were rated as "partially incorrect" or "completely incorrect." For ChatGPT4, these figures were 68.3% and 31.7%, respectively. The difference in accuracy ratings between the two versions was not statistically significant (chi-square test, Conclusion: As over a quarter of responses contained expert-identified inaccuracies, the current performance of ChatGPT is insufficient for safe and reliable use in clinical decision-making. Nevertheless, it has potential to expand health information access for parents. However, these findings should be interpreted with caution given the small sample size and potential selection bias regarding parents' educational backgrounds. Future improvements should enhance accuracy, clarity, and integration between parents and healthcare professionals.

Indexed as

artificial intelligenceChatGPTgeneral-purpose LLMsparentingPediatric healthcaresafety

Identifiers

PMID41836613
PMCPMC12979900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.