Evidence map›Paper›PMID 41836366›Full record

ArticleBrain behavior and immunity integrative2023

Effects of group trauma-sensitive yoga on inflammatory markers and psychological well-being in women veterans with PTSD: A randomized controlled trial.

Belle Zaccari, Ursula A Kelly, Travis I Lovejoy, Kimberly Hubbard, Aurora Newman, Jennifer M Loftis

Abstract read
In one paragraph

Article in Brain behavior and immunity integrative, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Belle ZaccariVA Portland Health Care System, Portland, OR, United States.
Ursula A KellyAtlanta VA Health Care System, Decatur, GA, United States.
Travis I LovejoyVA Portland Health Care System, Portland, OR, United States.
Kimberly HubbardVA Portland Health Care System, Portland, OR, United States.
Aurora NewmanVA Portland Health Care System, Portland, OR, United States.
Jennifer M LoftisVA Portland Health Care System, Portland, OR, United States.

Funding

AHRQ HHS K12 HS026370BLRD VA I01 BX002061CSRD VA I01 CX002668HSRD VA I01 HX001087
6 · The paper itself

Abstract

Background: Lifetime prevalence of post-traumatic stress disorder (PTSD) is double among veterans compared to civilians and women compared to men. Inflammatory factors are increasingly implicated in symptoms of PTSD. Yoga shows promise to reduce psychological symptoms of PTSD and positively impact inflammatory responses. The present study aimed to examine the effectiveness of yoga to reduce symptoms of PTSD and depression in addition to investigating the impact of treatment on inflammatory markers in women veterans with PTSD secondary to military sexual trauma. Methods: We collected dried blood spot samples, self-report and clinician administered measures of PTSD, and self-reported depression symptoms at baseline, 2 weeks, and 3 months post-intervention from a subset of women veterans diagnosed with PTSD (N = 27) who were randomized to either Trauma Center Trauma-Sensitive Yoga (TCTSY; a movement therapy) or cognitive processing therapy (CPT; a talk therapy) as part of a larger multisite RCT. Concentrations of interleukin (IL)-6, IL-10, and C-reactive protein (CRP) were measured using multiplex bead-based immunoassay at baseline and post-intervention (2 weeks and 3 months). Generalized estimating equations examined changes in symptoms of PTSD, depression, and inflammatory markers over time. We hypothesized decreases in IL-6 and CRP and increases in IL-10 in TCTSY participants compared to CPT participants and that PTSD and depression symptoms would improve over time in both groups. Results: From baseline to 3 months post-intervention, IL-6 (β = 0.10, Conclusions: Findings indicate that TCTSY has the potential to improve symptoms of PTSD and depression and alter inflammatory markers. The findings are limited by our sample size and the immune factors we examined. Future directions for related research would benefit from measuring a wider array of stress response components.

Indexed as

Cognitive processing therapyCRPIL-10IL-6Inflammatory markersPosttraumatic stress disorderSexual traumaTrauma-sensitive yogaWomen veterans

Identifiers

PMID41836366
PMCPMC12981235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.