Evidence map›Paper›PMID 41836316›Full record

ArticleFrontiers in aging2026

Ectoine attenuates H

Meini Li, Jingyue Zhang, Wenke Yang, Zengqiang Miao, Yanran Pai, Yi Yi, Jie Shuang, Xiang Gao, Yongzhen Li

Abstract read
In one paragraph

Article in Frontiers in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meini Li *Department of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Jingyue Zhang *Department of Clinical Laboratory, Eighth Affiliated Hospital of Guangxi Medical University, Guigang City People's Hospital, Guigang, Guangxi, China.
Wenke YangDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Zengqiang MiaoDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Yanran PaiDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Yi YiDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Jie ShuangDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Xiang GaoDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Yongzhen LiDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ectoine ((S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) is a major compatible solute found in halophilic microorganisms from salt lakes. The anti-cellular senescence effect and skin safety of Ectoine on H Methods: An oxidative stress senescence model was established using H Results: Exposure to H Conclusion: Ectoine exerts potent anti-senescence effects in H

Indexed as

cellular senescenceEctoineHaCaToxidative stressp53/p21

Identifiers

PMID41836316
PMCPMC12979466

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.