ArticleACS nano medicine2026
A Renally Excretable Gold Nanoparticle Oncology Platform Enabling Effective Photothermal Therapy and Chemotherapy Combination.
Article in ACS nano medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- pH-Dependent Silica Nanoshell Degradation Influences SERRS Enhancement in Biological Environments.ACS measurement science au · 2026Article
- Multifunctional Nano-Contrast Agent Carriers: From Traditional Platforms to Next-Generation Theranostic Applications in Molecular Imaging.Biomedicines · 2026Review
- Application Advances of Gold Nanoparticles in Cancer Theranostics: From Physicochemical Mechanisms to Multifunctional Nanoplatforms.International journal of molecular sciences · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combination therapies have largely replaced monotherapies in oncology. Thermal therapy has been developed as an adjunctive treatment owing to its safety and high compatibility with established theraypy options. However, bulky equipment and non-standardized protocols have limited its clinical use. The emergence of gold nanoparticle (AuNP)-based photothermal therapy (PTT) offers a simpler approach using injectable formulations and portable near-infrared (NIR) laser devices. However, poor excretion of AuNPs raises safety concerns and hinders translation. Here, we designed a gold nanoplatform that retains the photothermal capacity of AuNPs while enabling efficient excretion. Ultrasmall AuNPs (<6 nm) with a hydrophilic coating may be renally cleared, but clustering normally alters biodistribution and results in long-term hepatic deposition, prior to excretion. In this study, we employed
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Registered trials
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