Evidence map›Paper›PMID 41836293›Full record

ArticleFrontiers in cell and developmental biology2026

Yuanyuan Wang, Keyi Lu, Yuhang Gong, Yanna Shao, Siqi Liu, Yuan Fang, Yifan Shi, Erping Xu, Yanqiong Yang, Si Yuan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Unveiling the Value ofFoods (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuanyuan WangCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Keyi LuCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Yuhang GongCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Yanna ShaoCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Siqi LiuCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Yuan FangShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yifan ShiCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Erping XuCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Yanqiong YangNujiang Lisu Autonomous Prefecture Traditional Chinese Medicine Hospital, Nujiang, Yunnan, China.
Si YuanNujiang Lisu Autonomous Prefecture Traditional Chinese Medicine Hospital, Nujiang, Yunnan, China.
Ming BaiCollaborative Innovation Center of Research and Development on The Whole Industry Chain of Yu-Yao, Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Zhibin WangDepartment of Critical Care Medicine, School of Anesthesiology, Naval Medical University, Shanghai, China.
Bo ZhangShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necroptosis, a form of programmed cell death, plays a significant role in compromising the intestinal barrier and initiating intestinal inflammation. An analysis of data from the Gene Expression Omnibus (GEO) reveals a strong correlation between ulcerative colitis (UC) and the pathological mechanisms of necroptosis. Consequently, inhibiting necroptosis may offer a promising strategy for ameliorating UC. Cao Guo (CG), a traditional Chinese medicine extensively utilized in China for both dietary and medicinal purposes, is frequently included in classical prescriptions for UC treatment. However, the precise chemical constituents of CG and its potential therapeutic targets for UC remain inadequately characterized. In this study, we analyzed the chemical composition of CG, employed a classic necroptosis model to assess the anti-necroptosis activity of CG, and conducted validation using a mouse model of UC. Through bioinformatics analysis and other methodologies, we initially explored the potential targets of CG in UC treatment and conducted subsequent verification. The findings demonstrate that in an

Indexed as

Amomum tsaokobioinformatics analysisnecroptosisSTAT3ulcerative colitis

Identifiers

PMID41836293
PMCPMC12979518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.