ArticleOrthopedic reviews2026
Commonly Used Opioids in the Orthopedic Operating Room: A Narrative Review.
Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Popliteal Plexus Block as a Potential Alternative to IPACK Block in Total-Knee Arthroplasty: Anatomical Rationale, Clinical Evidence, and Ergonomic Advantages.Journal of clinical medicine · 2026Review
- Novel 2-Benzylbenzimidazole Opioids: Emerging Drugs of Abuse and Pharmacological Considerations with Nitazene Analogs.Current pain and headache reports · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthopedic surgical procedures are consistently associated with significant postoperative pain due to extensive tissue manipulation, osseous injury, and inflammatory responses. Effective perioperative analgesia is therefore fundamental to successful orthopedic outcomes, influencing early mobilization, complication rates, length of hospital stay, and patient satisfaction. Although opioid-sparing and enhanced recovery after surgery (ERAS) pathways have gained popularity, opioids remain central to analgesic management in orthopedic operating rooms. This narrative review examines the opioids most commonly used in orthopedic perioperative care, including fentanyl, morphine, remifentanil, hydromorphone, oxycodone, sufentanil, and methadone. Emphasis is placed on pharmacologic properties, clinical indications, dosing considerations, adverse effects, and comparative evidence in orthopedic populations. In addition, the evolving role of opioids within multimodal analgesia frameworks is discussed, with attention to balancing effective pain control against opioid-related risks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.