Evidence map›Paper›PMID 41836181›Full record

ArticleOrthopedic reviews2026

Perioperative Use of Benzodiazepines in Orthopedic Surgery: A Brief Narrative Review.

Anvinh Nguyen, Joseph Donnelly, Tommy Li, Jamal Hasoon

Abstract read
In one paragraph

Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anvinh NguyenDepartment of Anesthesiology Baylor College of Medicine.
Joseph DonnellyDepartment of Anesthesiology Baylor College of Medicine.
Tommy LiDepartment of Anesthesiology Baylor College of Medicine.
Jamal HasoonDepartment of Anesthesiology, Critical Care, and Pain Medicine The University of Texas Health Science Center at Houston.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benzodiazepines are frequently administered in orthopedic anesthesia for anxiolysis, sedation, amnesia, and seizure prophylaxis. Their role continues to evolve with the growing use of regional anesthesia, outpatient joint procedures, and enhanced recovery after surgery (ERAS) pathways. This narrative review examines the pharmacology, mechanisms of action, clinical indications, contraindications, and key clinical studies of benzodiazepines commonly used in the operating room in the United States, with a specific focus on their application in orthopedic surgical practice.

Indexed as

amnesiaanxiolysisbenzodiazepinesenhanced recovery after surgeryERASorthopedic anesthesiaoutpatient orthopedic surgeryperioperative sedationregional anesthesia

Identifiers

PMID41836181
PMCPMC12988847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.