Evidence map›Paper›PMID 41835940›Full record

ArticleFrontiers in neuroscience2026

Retinal hemodynamic effects of sub-Tenon anesthesia.

Anthia Papazoglou, Tim J Enz, Ulrike Steitz, Muriel Dysli, Markus Tschopp

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anthia PapazoglouDepartment of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland.
Tim J EnzDepartment of Ophthalmology, University of Basel, Basel, Switzerland.
Ulrike SteitzDepartment of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland.
Muriel DysliDepartment of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland.
Markus TschoppDepartment of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and objectives: Sub-Tenon anesthesia techniques are commonly employed in ophthalmology. However, there is speculation that these techniques may have hemodynamic effects on the eye, potentially affecting patients with impaired ocular perfusion. This study aims to evaluate the impact of sub-Tenon anesthesia during cataract surgery on retinal vessel density (VD) and perfusion density (PD) in eyes affected by diabetic maculopathy (DM) or retinal vein occlusion (RVO), using optical coherence tomography angiography (OCTA). Methods: The study included 20 patients receiving sub-Tenon anesthesia with unpreserved mepivacaine 2% for unilateral cataract surgery: 10 with DM and 10 with RVO, analyzing a total of 40 eyes (20 treated and 20 untreated). Blood pressure, intraocular pressure (IOP), and retinal microvascular changes measured via OCTA (VD, PD) were documented before and shortly after sub-Tenon anesthesia. The contralateral eye, which did not receive anesthesia, served as a control. Results: A negative association between sub-Tenon anesthesia to VD and PD was observed, with a VD-change of -1.5 ± 2.8 mm/mm Conclusion: This study did not prove retinal microvascular changes associated with sub-Tenon anesthesia. The observed VD and PD reductions were likely caused by OCTA image artifacts rather than true hemodynamic changes.

Indexed as

cataract surgerydiabetesintraocular pressurelocal anesthesiamepivacaineperfusionretinopathysub-Tenon

Identifiers

PMID41835940
PMCPMC12982183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.