Evidence map›Paper›PMID 41835932›Full record

ArticleBMJ public health2026

Pregnancy rates among users of combined oral contraceptives in Aotearoa New Zealand in 2019: a nationwide retrospective cohort study.

Caryn Thomas, Nicholas Bowden, Rhiannon Braund, Jesse Kokaua, Matthew Hobbs, Helen Paterson

Abstract read
In one paragraph

Article in BMJ public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caryn ThomasDepartment of Obstetrics, Gynaecology, and Women's Health | Oranga Wāhine, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0003-3837-5476
Nicholas BowdenDepartment of Paediatrics and Child Health, University of Otago, Dunedin, New Zealand.
Rhiannon BraundPharmacy and Biomedical Sciences, Te Huataki Waiora - School of Health, The University of Waikato, Hamilton, New Zealand.
Jesse KokauaVa'a o Tautai - Centre for Pacific Health, Division of Health Sciences, University of Otago, Dunedin, New Zealand.
Matthew HobbsFaculty of Health, University of Canterbury, Christchurch, Canterbury, New Zealand.
Helen PatersonDepartment of Obstetrics, Gynaecology, and Women's Health | Oranga Wāhine, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-8240-082X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pregnancy rates amongst users of combined oral contraceptives (COCs) in Aotearoa New Zealand (Aotearoa/NZ) are unknown. Filling this gap aims to help guide future research and initiatives for achieving equitable contraceptive services in Aotearoa/NZ. Objective: To estimate the rate of pregnancy among users of COCs in Aotearoa/NZ in 2019, and explore correlates of pregnancy rate across sociodemographic and geographic factors. Methods: This retrospective cohort study used whole-of-population data from the Integrated Data Infrastructure, a research database containing deidentified routinely collected government data. Users of COCs were identified using pharmaceutical dispensing data, and pregnancy events were identified in maternity and hospital discharge datasets. Pregnancy events were included if they were estimated to have been conceived during a period of COC use. Observed pregnancy rates were calculated for the entire study population, new and established users, and sociodemographic and geographic subgroups. Rates were analysed using Poisson regression models to produce comparative risk ratios and 95% CIs that were adjusted for covariates. Results: A pregnancy rate of 3.50 per 100 person-years of COC use was identified from a cohort of 208 197 individuals using COCs in Aotearoa/NZ in 2019. There was significant variation in pregnancy rates by several key sociodemographic and geographic factors including by whether a user was new/restarting or established (reference) on COCs (adjusted risk ratio 1.28, 95% CI 1.19 to 1.37), or lived in a rural or urban (reference) area (adjusted risk ratio 1.32, 95% CI 1.21 to 1.44). There were also significant differences in pregnancy rate by age group, ethnicity, parity, highest qualification, household income, and neighbourhood deprivation. Conclusions: The estimated pregnancy rate among users of COCs in Aotearoa/NZ is comparable to international findings. Sociodemographic and geographic variation in pregnancy rates may be explained by inconsistent pill use, access barriers, contraceptive failure, and early discontinuation of COCs with intended pregnancy conception. An opportunity remains for further research to fully understand the drivers of such variation. Nevertheless, these findings will inform family planning services, clinical practice, and public health policy. Furthermore, they have implications for whether healthcare services are providing equitable contraceptive care and meeting the needs of contraceptive users.

Indexed as

PharmacoepidemiologyPharmacovigilanceSexual Health

Identifiers

PMID41835932
PMCPMC12983885

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.